过去一年中添加的文章,按日期排序

Mitochondrial Dysfunction in Adipose Tissue and its Implication in the Onset of Type 2 Diabetes

TA GUARACA MEDINA - thesis.unipd.it
2 天前 - … by deficient production and secretion of insulin, has been … mitochondria; their
dysfunction triggers insulin resistance … nutrient availability diminishes mitochondrial function and …

Interaction between the Neuroprotective and Hyperglycemia Mitigation Effects of Walnut-Derived Peptide LVRL via the Wnt3a/β-Catenin/GSK-3β Pathway in a Type 2 …

F Zhao, L Guo, T Huang, C Liu, D Wu… - Journal of Agricultural …, 2024 - ACS Publications
10 天前 - … in glucose-induced insulin resistance in PC12 cells. In vitro … and rescue learning
and memory deficiencies. Hou et al. … between mitochondria and T2DM, and mitochondrial

The role and mechanism of VDAC1 in type 2 diabetes: An underestimated target of environmental pollutants

Y Ma, X Sun, X Yao - Mitochondrion, 2024 - Elsevier
12 天前 - … due to insulin resistance or insulin deficiency. With … , regulates signal transduction
between mitochondria and … into and from mitochondria, modulating insulin secretion. We …

Proprotein convertase subtilisin/kexin type 9 deficiency in extrahepatic tissues: emerging considerations

F Lu, E Li, X Yang - Frontiers in Pharmacology - frontiersin.org
12 天前 - … Consequently, PCSK9 deficiency may harm extrahepatic … , mitochondrial impairment,
insulin resistance, and … disorders arising from PCSK9 deficiency in extrahepatic tissues. …

[HTML][HTML] Distinct and Additive Effects of Alcohol and Thiamine Deficiency in the Developing Brain: Relevance to Fetal Alcohol Spectrum Disorder

SM de la Monte, E Silbermann, M Tong - Journal of Behavioral and Brain …, 2024 - scirp.org
12 天前 - … However, the role of thiamine deficiency as a distinct or additive factor in the …
thiamine deficiency on ethanol-mediated neurotoxicity, mitochondrial dysfunction, insulin resistance

Deletion of miPEP in adipocytes protects against obesity and insulin resistance by boosting muscle metabolism.

A Diaz-Vegas, KC Cooke, HB Cutler, B Yau… - Molecular …, 2024 - Elsevier
19 天前 - Insulin resistance, characterised by a deficiency in insulin-mediated glucose transport
into … have shown that insulin resistance leads to alterations in the mitochondrial proteins, …

[HTML][HTML] Early changes of glia cells in the INSC94Y pig model for diabetic retinopathy

A Grosche, L Kaplan, O Bludau… - … & Visual Science, 2024 - iovs.arvojournals.org
33 天前 - … such as hyperglycemia and insulin resistance can lead to … , which mimics severe
insulin-deficient diabetes (SIDD), … We also assessed their mitochondrial health using the JC-…

Low-Iron Diet-Induced Fatty Liver Development Is Microbiota Dependent and Exacerbated by Loss of the Mitochondrial Iron Importer Mitoferrin2

KA Klag, R Bell, X Jia, A Seguin, JA Maschek… - Nutrients, 2024 - mdpi.com
42 天前 - … metabolism and increased insulin resistance that was … We report that total body
loss of mitochondrial iron importer … of iron deficiency (a low-iron diet) and altered mitochondrial

COMMD10-deficiency in adipose tissue macrophages attenuates obesity and insulin resistance by boosting mitochondrial and antioxidant functions

N Gluck, S Ben-Shlomo, BA Shrkihe, Y Radenbazarov… - 2024 - researchsquare.com
44 天前 - … 2d), indicating improved local insulin signaling. Aberrant lipid storage and
mobilization in adipose tissue induces insulin resistance. Hence, we determined adipose tissue …

MARK4 aggravates cardiac dysfunction in mice with STZ-induced diabetic cardiomyopathy by regulating ACSL4-mediated myocardial lipid metabolism

Y Wu, J Zhang, W Wang, D Wu, Y Kang, L Fu - Scientific Reports, 2024 - nature.com
44 天前 - … secretion in the mice were observed through an intraperitoneal insulin resistance
test. … MARK4 deficiency can promote mitochondrial fusion and protect mitochondrial function …