Insulin resistance: Review of the underlying molecular mechanisms

H Yaribeygi, FR Farrokhi, AE Butler… - Journal of cellular …, 2019 - Wiley Online Library
… of mechanisms, including insulin resistance (IR), beta cell dysfunction and apoptosis with
lower circulatory insulin … In the current review, the most important mechanisms underlying the …

Molecular mechanisms of insulin resistance

S Schinner, WA Scherbaum, SR Bornstein… - Diabetic …, 2005 - Wiley Online Library
insulin resistance is still largely unknown, recent studies have contributed to a deeper
understanding of the underlying molecular mechanisms. … models and insulin resistant patients has …

[PDF][PDF] Molecular mechanisms of insulin resistance: An update

C Gutiérrez-Rodelo, A Roura-Guiberna… - Gac Med …, 2017 - researchgate.net
Insulin resistance is one of the main characteristics of … promote insulin resistance. The aim
of this review is to elucidate the molecular aspects of insulin resistance and the mechanisms

Molecular mechanism of insulin resistance

S Bhattacharya, D Dey, SS Roy - Journal of biosciences, 2007 - Springer
… : molecular mechanisms of insulin resistance. Lesson from patients with mutations in the
insulin… Protein–protein interaction in insulin signaling and the molecular mechanisms of insulin

Molecular mechanisms of insulin resistance and associated diseases

B Mlinar, J Marc, A Janež, M Pfeifer - Clinica chimica acta, 2007 - Elsevier
… role in insulin resistance are … insulin resistance may be implicated in the development of
many pathological states, such as hypertension and hyperandrogenaemia. Insulin resistance

Molecular mechanisms of insulin resistance and the role of the adipocyte

GS Hotamisligil - International Journal of Obesity, 2000 - nature.com
Insulin resistance is a common feature of obesity and … However, the molecular mechanisms
underlying abnormal insulin … the molecular basis of these disorders. The role of TNFa in …

[HTML][HTML] Molecular mechanism of insulin resistance in obesity and type 2 diabetes

K Choi, YB Kim - The Korean journal of internal medicine, 2010 - ncbi.nlm.nih.gov
… at least in part, from impaired insulin-dependent PI3K activation and … molecular basis of
skeletal muscle insulin resistance in obesity and type 2 diabetes. In addition, the effects of insulin-…

[HTML][HTML] Molecular mechanisms of insulin resistance in type 2 diabetes mellitus

V Saini - World journal of diabetes, 2010 - ncbi.nlm.nih.gov
… Although the precise pathophysiological sequence which leads to insulin resistance is still
… of the underlying molecular mechanisms. This review deals with the mechanisms related to …

[HTML][HTML] Mechanisms of insulin action and insulin resistance

MC Petersen, GI Shulman - Physiological reviews, 2018 - journals.physiology.org
… promotes PP1 targeting to glycogen particles and increases PP1 activity towards GS, but
the specific molecular mechanisms responsible for this activity are incompletely understood (…

Molecular mechanisms of insulin resistance that impact cardiovascular biology

CCL Wang, ML Goalstone, B Draznin - Diabetes, 2004 - Am Diabetes Assoc
… to stimulate the mitogenic insulin-signaling … insulin resistance and mechanisms of potentially
detrimental influence of hyperinsulinemia in the presence of metabolic insulin resistance