Current concepts in insulin resistance, type 2 diabetes mellitus, and the metabolic syndrome

JEB Reusch - The American journal of cardiology, 2002 - Elsevier
… of insulin resistance in patients with type 2 diabetes. Agents such as thiazolidinediones,
which improve insulin sensitivity, … sequelae associated with insulin resistance. Newer findings …

[HTML][HTML] Insulin resistance, type 1 and type 2 diabetes, and related complications 2017

JF Ndisang, A Vannacci, S Rastogi - Journal of diabetes research, 2017 - ncbi.nlm.nih.gov
diabetes is … insulin resistance, type 1 diabetes, type 2 diabetes, and related cardiometabolic
complications. A common pathophysiological destructive force in type 1 and type 2 diabetes

Insulin resistance as the core defect in type 2 diabetes mellitus

BJ Goldstein - The American journal of cardiology, 2002 - Elsevier
… In addition to causing hyperglycemia in type 2 diabetes, insulin resistance and … the
interplay between insulin resistance, β-cell function, and the development of type 2 diabetes. In …

The importance of insulin resistance in the pathogenesis of type 2 diabetes mellitus

WY Fujimoto - The American journal of medicine, 2000 - Elsevier
… , insulin resistance is essential to the development of the majority of cases of type 2 diabetes
in the prevalence of insulin resistance and type 2 diabetes in various ethnic populations that …

Relationships among insulin resistance, type 2 diabetes, essential hypertension, and cardiovascular disease: similarities and differences

GM Reaven - The journal of clinical hypertension, 2011 - Wiley Online Library
… Glucose intolerance, the dyslipidemia associated with insulin resistance, and essential …
the role that insulin resistance plays in the pathogenesis of type 2 diabetes and essential …

Mechanisms linking obesity to insulin resistance and type 2 diabetes

SE Kahn, RL Hull, KM Utzschneider - Nature, 2006 - nature.com
… the reduced efficiency of insulin action, thereby … and insulin resistance to be associated
with type 2 diabetes, β-cells must be unable to compensate fully for decreased insulin sensitivity

Pathogenesis of type 2 diabetes: insulin resistance

G Boden - Endocrinology and metabolism clinics, 2001 - endo.theclinics.com
… by insulin secretion. Hence, insulin resistance alone will not result in type 2 diabetes without
… The exceptions to this rule are extremely rare instances in which insulin resistance reaches …

Insulin resistance in type 2 diabetes: role of fatty acids

P Arner - Diabetes/metabolism research and reviews, 2002 - Wiley Online Library
insulin resistance. This article focuses on the role of FFAs in insulin resistance in type 2
diabetes. … ‘glitazones’ have direct effects on insulin resistance and it is believed that these effects …

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

BC Martin, JH Warram, AS Krolewski, JS Soeldner… - The Lancet, 1992 - Elsevier
… range of insulin secretion values. Obesity is associated with insulin resistance and a high
incidence of type 2 diabetes.2.3,5,6 As expected, the subjects who developed diabetes were …

Insulin resistance syndrome and type 2 diabetes mellitus

DW Erkelens - The American journal of cardiology, 2001 - Elsevier
… In most cases, diabetic dyslipidemia is preceded by hyperinsulinemia resulting from insulin
resistance. Because patients with type 2 diabetes and insulin resistance are at a markedly …