An integrative, multi‐scale, genome‐wide model reveals the phenotypic landscape of Escherichia coli

J Carrera, R Estrela, J Luo, N Rai… - Molecular systems …, 2014 - embopress.org
… the integrative genome‐scale model of Escherichia coli in which EBA with experimental and
inferred interactions predicted gene expression profiles. PCC corresponds to the correlation …

Comparative multi-omics systems analysis of Escherichia coli strains B and K-12

SH Yoon, MJ Han, H Jeong, CH Lee, XX Xia, DH Lee… - Genome biology, 2012 - Springer
analyses of transcriptomes, proteomes, and phenomes can complement each other and be
integrated to … Furthermore, the multidimensional omics data can be integrated to reconstruct …

Genetic and biochemical analysis of the integration host factor of Escherichia coli

G Mengeritsky, D Goldenberg, I Mendelson… - Journal of molecular …, 1993 - Elsevier
Integration host factor (IHF) is a small, heterodimeric DNA-binding protein of Escherichia coli
composed of two subunits, α and β, encoded by the himA and hip genes, respectively. IHF …

In vivo analysis of integration of membrane proteins in Escherichia coli

K Ito, Y Akiyama - Molecular microbiology, 1991 - Wiley Online Library
… methodology to assess the integration states of newlysynthesized membrane proteins of E.
… to provide ground work for the in vivo analysis of membrane protein integration. Specifically, …

Identification of Potential Transcriptional Biomarkers Differently Expressed in Both S. aureus‐ and E. coli‐Induced Sepsis via Integrated Analysis

H Chen, Y Li, T Li, H Sun, C Tan, M Gao… - BioMed Research …, 2019 - Wiley Online Library
… aureus- and E. coli-induced sepsis, we have analyzed four microarray datasets from GEO
database and integrated results with bioinformatics tools. 42 and 54 DEGs were identified in …

Novel microRNA involved in host response to avian pathogenic Escherichia coli identified by deep sequencing and integration analysis

X Jia, Q Nie, X Zhang, LK Nolan… - Infection and …, 2017 - Am Soc Microbiol
Avian pathogenic Escherichia coli (APEC) causes one of the most common bacterial
diseases of poultry worldwide. Effective control methods are therefore desirable and will be …

Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli

KW George, MG Thompson, J Kim, EEK Baidoo… - Metabolic …, 2018 - Elsevier
… to study IPP toxicity in isoprenol-producing Escherichia coli. We first characterize the physiological
… Next, using multi-omics data, we demonstrate that endogenous E. coli metabolism is …

Multi-omics integration accurately predicts cellular state in unexplored conditions for Escherichia coli

M Kim, N Rai, V Zorraquino, I Tagkopoulos - Nature communications, 2016 - nature.com
… Indeed, for Escherichia coli we have only 33 samples with the trifecta of transcriptome,
proteome and metabolome, and even in those cases, not simultaneously. In addition, many data …

Integrated transcriptomic and proteomic analysis of the physiological response of Escherichia coli O157: H7 Sakai to steady-state conditions of cold and water activity …

C Kocharunchitt, T King, K Gobius, JP Bowman… - Molecular & Cellular …, 2012 - ASBMB
An integrated transcriptomic and proteomic analysis was undertaken to determine the
physiological response of Escherichia coli O157:H7 Sakai to steady-state conditions relevant to …

Integrated network analysis identifies nitric oxide response networks and dihydroxyacid dehydratase as a crucial target in Escherichia coli

DR Hyduke, LR Jarboe, LM Tran… - Proceedings of the …, 2007 - National Acad Sciences
… reaction mechanisms and phenotypic data from genetic knockouts to identify active chemistry
and direct NO targets in Escherichia coli. This approach identified the comprehensive E. …