… Our results therefore describe the first nucleotide-resolution genome/transcriptome-wide
integrated analysis of LOH and MAE in a population of breast tumors and the landscape of allele…

… This observation led to the suggestion that many of the analyzed chromosomes might
have a baseline CN greater than two. Here, we perform an integrated analysis of GBM tumors …

… The integration analysis of copy number changes and LOH alterations was conducted via …
The integration analysis revealed a sum of 73 MCORs in this category, in which these regions …

… Methods: We analyzed genome-wide copy number alterations and loss of heterozygosity
(LOH) in 25 established pancreatic cancer cell lines using a high-density single nucleotide …

… Loss of heterozygosity (LOH) is a common genetic event in cancer development, and is
known to be involved in the somatic loss of wild-type alleles in many inherited cancer syndromes…

… Some of the identified molecular markers—such as loss of heterozygosity (LOH) on …
This review summarizes recent developments in the molecular analysis of malignant glioma…

… marker analysis for the detection of loss of heterozygosity (LOH). … Integration of these 3
platforms allows detection of genomic … , integrated copy number and gene expression analyses …

… We then integrated each of these analyses to characterize the potential druggability landscape
of these protein-altering GEMINI vulnerabilities. Every variant was given a score from 0 to …

… limited input DNA has further enhanced the power of concurrent LOH and CGH analysis.
The integration of these technologies permits genome-wide profiling of a selected pure disease …

… of allele-specific loss of heterozygosity (LOH) for the localization of CRC susceptibility genes,
we initially conducted a genome-wide allelotyping analysis of 48 adenomas from a patient …