Integrative analysis of DNA methylation and gene expression identified follicular thyroid cancer-specific diagnostic biomarkers

Y Yao, P Xu, T Ying, Y Wang, X Wang, L Shu… - Frontiers in …, 2022 - frontiersin.org
… we performed an integrative analysis of DNA methylation and RNA array data from our own
cohort (14 Follicular thyroid carcinoma vs 16 Benign thyroid lesion) to identify thyroid cancer-…

Recurrence of papillary thyroid cancer: a systematic appraisal of risk factors

HR Nieto, CEM Thornton, K Brookes… - The Journal of …, 2022 - academic.oup.com
… 46 of 501 reported papillary thyroid cancers (PTC) had recurred; our appraisal of gene
mutation, gene expression and miR expression revealed that tumor recurrence was not likely to …

Characterizing dedifferentiation of thyroid cancer by integrated analysis

H Luo, X Xia, GD Kim, Y Liu, Z Xue, L Zhang, Y Shu… - Science …, 2021 - science.org
thyroid cancer (ATC) cells were derived from a small subset of papillary thyroid cancer (PTC…
on ATC development was revealed by integrated analyses of copy number alteration and …

Integrative metabolomic characterization identifies plasma metabolomic signature in the diagnosis of papillary thyroid cancer

S Yu, C Liu, Y Hou, J Li, Z Guo, X Chen, L Zhang… - Oncogene, 2022 - nature.com
… from thyroid nodules poses challenges in clinical practice. We aimed to identify the plasma
metabolomic biomarkers in discriminating papillary thyroid cancer (PTC) from benign thyroid

Recurrence-associated genes in papillary thyroid cancer: An analysis of data from The Cancer Genome Atlas

MN Chien, PS Yang, JJ Lee, TY Wang, YC Hsu… - Surgery, 2017 - Elsevier
thyroid dedifferentiation. The incidence of thyroid cancer, particularly papillary thyroid cancer,
Papillary thyroid cancer tends to be biologically indolent and has an excellent prognosis. …

Network analyses of integrated differentially expressed genes in papillary thyroid carcinoma to identify characteristic genes

J Shang, Q Ding, S Yuan, JX Liu, F Li, H Zhang - Genes, 2019 - mdpi.com
… The morbidity rate of papillary thyroid carcinoma (PTC) ranks the highest among thyroid
cancer. Exploring the cause and underlying molecular events of PTC has become a hot topic [1], …

Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary thyroid carcinoma

T Wang, J Shi, L Li, X Zhou, H Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
… Results: Our integrative analysis of thyroid follicular cells revealed 42 signaling pathways
enriched in malignant follicular cells, including cytokine–cytokine receptor interaction, PI3K/Akt …

Identification of a six gene prognosis signature for papillary thyroid cancer using multi-omics methods and bioinformatics analysis

H Ren, X Liu, F Li, X He, N Zhao - Frontiers in Oncology, 2021 - frontiersin.org
… The most common subtype is papillary thyroid cancer (PTC), accounting for about 80% of all
THCAs (4). … As a result, a comprehensive analysis of integrated gene expression data using …

Integrated metabolic and genetic analysis reveals distinct features of human differentiated thyroid cancer

E Cararo Lopes, A Sawant, D Moore… - Clinical and …, 2023 - Wiley Online Library
… importance of integrated omics for thyroid cancer diagnosis, … methods to diagnose differentiated
thyroid cancer when the … to help predict high-risk papillary thyroid cancer. Both may be …

[HTML][HTML] Bioinformatics analysis to screen key genes in papillary thyroid carcinoma

Y Liu, S Gao, Y Jin, Y Yang, J Tai… - Oncology …, 2020 - spandidos-publications.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid carcinoma, and its
incidence has been on the increase in recent years. However, the molecular mechanism of PTC …