… sought to demonstrate a physical interaction between the two molecules and to define the
… (B) Two-dimensional SDS–PAGE analysis of material precipitated with anti-DR serum from …

… II molecules, with the major differences concentrated in the region equivalent to the peptide
binding site, which in HLA-… general region of HLA-DR in interactions with HLA-DM. Tethered …

… Crystals have been grown from a number of class II HLADR (… the weak dimerization sites of
DR 1 and of the TCR molecules … fic, interaction between the af chains of TCR and HLA into a …

… TCR–HLA interaction site. Hence, the possibility had existed that even gp42-complexed
class II molecules could present antigen to specific T cells. Here, the use of HLA-DR tetramers …

… interaction sites for DRBl"1501 and DRB5*0101, respectively, that may contribute to its
immunodominance. Because HLA… interaction between potential autoantigenic peptides and these …

… It connects the α 1 and α 2 domains in its noncharged form by hydrophobic interactions with
… As expected SDS/PAGE analysis did not reveal any significant differences between the two …

… To examine the role of these paired dimorphisms in NKIR–HLA-C interactions, we
carried out site-directed mutagenesis to change αAla-73 to αThr-73 in both Cw6 and Cw7 (Cw6/A73T, …

… The existence of two interaction sites on SEA for HLADR vs the one site found in SEB
and TSST-1 suggests that class II binding is important for bacterial virulence and/or survival …

… The purity of DM and DR in the eluted fractions was determined by SDS/PAGE followed
by silver staining (34). Only fractions estimated to be more than 90% pure were used in …

… the interaction site for the accessory molecule CD4. The lack of any detectable effect of
exchanging this region of the molecule … the human class I1 molecule interact with sufficiently high …