Interactive associations of vascular risk and β-amyloid burden with cognitive decline in clinically normal elderly individuals: findings from the Harvard Aging Brain …

JS Rabin, AP Schultz, T Hedden, A Viswanathan… - JAMA …, 2018 - jamanetwork.com
association of the FHS-CVD risk score with Aβ burden was only marginally significant. The
association … We next examined independent and interactive associations of the FHS-CVD risk …

Vascular risk and βamyloid are synergistically associated with cortical tau

JS Rabin, HS Yang, AP Schultz… - Annals of …, 2019 - Wiley Online Library
interactive association with subsequent tau burden in 2 predefined ROIs (EC and ITC). We
found a significant interaction … We did not find a significant interaction between FHS-CVD and …

Association of vascular risk factors with β-amyloid peptide and tau burdens in cognitively unimpaired individuals and its interaction with vascular medication use

T Köbe, J Gonneaud, AP Binette, PF Meyer… - JAMA network …, 2020 - jamanetwork.com
… When included in the same regression model, we found independent associations of Aβ
burden with LDL cholesterol level (β = 0.003 [SE, 0.001], P = .006) and pulse pressure (β = …

Associations of physical activity and β-amyloid with longitudinal cognition and neurodegeneration in clinically normal older adults

JS Rabin, H Klein, DR Kirn, AP Schultz… - JAMA …, 2019 - jamanetwork.com
β-Amyloid burden data used in the present study were obtained at baseline using carbon
11–… To do so, we added the 3-way interaction of FHS-CVD, Aβ, and time as well as the lower-…

Association of β-amyloid and vascular risk on longitudinal patterns of brain atrophy

JS Rabin, J Pruzin, M Scott, HS Yang, O Hampton… - Neurology, 2022 - AAN Enterprises
… , this should be reflected in significant associations when … examined whether the interactive
associations of vascular risk … to determine whether the interactive association of vascular risk …

[HTML][HTML] Interactive versus additive relationships between regional cortical thinning and amyloid burden in predicting clinical decline in mild AD and MCI individuals

FO Uquillas, HIL Jacobs, B Hanseeuw, GA Marshall… - NeuroImage: Clinical, 2018 - Elsevier
… We examined these associations in specific amyloid-… to investigate interactive and additive
effects of amyloid and … While previous studies have reported associations between CDR-SB …

Associations of widowhood and β-amyloid with cognitive decline in cognitively unimpaired older adults

KD Biddle, HIL Jacobs, FO Uquillas, BS Zide… - JAMA network …, 2020 - jamanetwork.com
… of cognitive change were further influenced by β-amyloid levels. We hypothesized an
interactive association of widowhood and β-amyloid with cognition in which widowhood would be …

Social engagement and amyloid-β-related cognitive decline in cognitively normal older adults

KD Biddle, FO Uquillas, HIL Jacobs, B Zide… - The American Journal of …, 2019 - Elsevier
associations of … amyloid-β or their interaction predicted poorer cognitive function over 3
years and, reciprocally, whether lower cognitive function, higher amyloid-β or their interaction

Independent and interactive influences of the APOE genotype and beta-amyloid burden on cognitive function in mild cognitive impairment

EH Seo, SH Kim, SH Park, SH Kang… - Journal of Korean …, 2016 - synapse.koreamed.org
… A lack of association between Aβ burden and cognition in AD dementia patients has been
… We did not find any associations of APOE ε4status or Aβ positivity with clinical or functional …

Association of cerebral amyloid-β aggregation with cognitive functioning in persons without dementia

…, H Zetterberg, Amyloid Biomarker Study Group - JAMA …, 2018 - jamanetwork.com
… , investigated the association between amyloid positivity and … included in the multicenter
Amyloid Biomarker Study. We also … age (β = 0.023 [95% CI, 0.009-0.037, P = .001 for interaction) …