The induction of interferon by levamisole in mice

S Matsubara, F Suzuki, N Ishida - Cellular Immunology, 1979 - Elsevier
… /kg of levamisole and assayed for antiviral activity (Fig. 1). The antiviral activity appeared by
… our hypothesis that T cells are involved in the IF induction produced by levamisole in mice. …

Potentiation by levamisole, methisoprinol, and adenine or adenosine of the inhibitory activity of human interferon against encephalomyocarditis virus

A Munoz, RA Garcia… - Antimicrobial agents and …, 1986 - Am Soc Microbiol
activity of human IFN against EMC virus. In summary, our results indicate that levamisole
infection induced by IFN in human HeLa cells. Interestingly enough, the combination of both …

Depressed natural killer cell activity in patients with hepatocellular carcinoma in vitro effects of interferon and levamisole

K Son, M Kew, AR Rabson - Cancer, 1982 - Wiley Online Library
… NK cell activity. When lymphocytes from patients or controls were treated for three hours
with human leukocyte interferon, NK cell activity was significantly improved. Levamisole did not …

[HTML][HTML] Levamisole induces interleukin-18 and shifts type 1/type 2 cytokine balance

CC Szeto, KM Gillespie, PW Mathieson - Immunology, 2000 - ncbi.nlm.nih.gov
… BN rats treated with levamisole showed a dose-dependent rise in serum IFN-γ and fall in …
IL-18, a recently characterized cytokine with potent activity in stimulating IFN-γ production. IL-12 …

Inhibition of interferon or soluble immune response suppressor (SIRS) mediated suppression by levamisole

TM Aune, CW Pierce - International Journal of Immunopharmacology, 1983 - Elsevier
… Treatment of SIRS or IFN/3 with levamisole had no effect on the subsequent ability of these
… with levamisole did not effect the suppressive activity of MeS-SF when added to spleen cells

Levamisole and interferon in children with chronic hepatitis B

M Ruiz-Moreno, R García, MJ Rua, B Serrano… - Hepatology, 1993 - journals.lww.com
… or to a spontaneous activation of the T cells induced by HBV. The increase in sIL-2R during
treatment with levamisole plus IFN paralleled an increase in serum ALT activity. This may be …

[PDF][PDF] Therapy for chronic hepatitis B with lymphoblastoid interferon‐α and levamisole

G Fattovich, G Giustina, L Brollo, M Guido… - …, 1992 - Wiley Online Library
IFN-a with immunomodulators appears to be a way to increase response rate. Levamisole is
known to enhance T-cell activity (4… with lymphoblastoid IFN-a and levamisole might be more …

Levamisole regulates the proliferation of murine liver T cells through Kupffer-cell-derived cytokines

JA Johnkoski, SM Peterson, RJ Doerr… - Cancer Immunology …, 1997 - Springer
… Here, we report that the proliferative activity of liver T cells from mice treated with levamisole
is modulated by increased production of interferon (IFN)α/β, interleukin-1 (IL-1), and IL-6 by …

Levamisole enhances immune response by affecting the activation and maturation of human monocyte-derived dendritic cells

LY Chen, YL Lin, BL Chiang - Clinical & Experimental …, 2008 - academic.oup.com
Levamisole-treated human DC also enhanced T cell activation towards type 1 T helper immune
response by inducing interferonactivity and become potent immunostimulatory cells that …

Immunomodulation with low dose levamisole in patients with colonic polyps

RF Holcombe, CE McLaren, T Milovanovic - Cancer Detection and …, 2006 - Elsevier
… blood mononuclear cells (PBMCs), measurement of interferon-… producing more PBMC-derived
interferon-γ and increasing … immune activity as well as specific assays of cellular immune …