… sensing mechanisms of SARS-CoV-2 and the mechanisms of SARS-CoV-2-mediated
inhibition of IFN responses. We also discuss the dysregulation of IFN responses in the context of …

… IFN-β treatment effectively blocks SARS-CoV-2 replication. In summary, our study shows
that SARS-CoV-2 perturbs host innate immune response via … the pathogenesis of SARS-CoV-2. …

… of the complex interplay between SARS-CoV-2 infection and the IFN system, highlighting
some … conserved IFN evasion strategies that are likely shared with SARS-CoV and MERS-CoV, …

… SARS-CoV typically does not induce an interferon response in infected cell cultures although
substantial amounts of the interferon… SARS-CoV is able to inhibit the induction of interferons…

… coronavirus termed SARS-CoV, employs multiple passive and active mechanisms to avoid
induction of the antiviral type I interferons in … The imbalance in the IFN response is thought to …

… indicators and reporting for IFN therapy for SARS-CoV-2 to improve evidence synthesis
and generation. While IFN therapy has the potential to be a viable treatment for SARS-CoV-2, …

… role of immune response to SARS-CoV-2 infection as well as recent publications on
characteristics and outcomes of COVID-19, and their relationship with interferons type I and type III. …

… lower IFN-ε and -ω relative expression levels. Overall, our findings contribute to recognize
components of a protective IFN response as a function of age, in the context of SARS-CoV-2 …

… Our results clearly show that induction of a robust IFN response in macrophages strongly
correlates with viremia (Supplementary Fig. 23A, B) and subsequent clearance of SARS-CoV-2 …

… SARS-CoV-2 proteins that suppress IFN-I response; (2) to determine at which step inhibition
occurs in the IFN-… among MERS-CoV, SARS-CoV, and SARS-CoV-2 of IFN-I production and …