… Such potential therapeutic agents are currently being applied to the treatment of rheumatoid
… in cancer treatment. Our focus here is on the metastatic and angiogenic properties of IL-1 …

… The clinical successes of targeting angiogenesis provide a basis for trials of interleukin-1
(IL-1) blockade and … [27] IL-1Ra treatment also reduced the expression of ICAM-1 and VCAM-…

… interleukin 1 receptor accessory protein … This review will focus on the current mechanistic
understanding of the inflammasome and IL-1 family cytokines in cancer and the clinical …

… -cancer treatments are able to promote IL-1β production by cancer or immune cells, with
opposite effects on cancer … question of whether or not to use IL-1β inhibitors in cancer treatment. …

… also has a number of properties potentially useful in the treatment of cancer, including direct
antiproliferative activity against certain human tumor cell lines and several murine tumors [5, …

… The interleukin-1 (IL-1) family is one of … in cancer has been well established in the past
decades. This review sets out to give an overview of the role of each IL-1 family member in cancer …

… Out of 26 enrolled patients only 20 completed the course of treatment [103]. We could not
find newer information regarding this agent in cancer treatment and larger trials must be …

BACKGROUND: Interleukin 1 (IL-1) is a pluripotent cytokine that promotes angiogenesis,
tumor growth, and metastasis in experimental models; its presence in some human cancers is …

… -1 (either ILla or IL-I@) for enhancing bone marrow recovery and for cancer treatment. The
IL-… Dynamics of interleukin 1 binding and internalization in T cells and fibroblasts. J. Immunol. …

… to single antiserum treatment suggesting that the two antibody treatments acted through a
… the progression of cancer cachexia. It seems as if the role of TNF and II -1 was to promote …