… Furthermore, the activation of the MAPK, NFκB, and IRF signaling pathways is a notable
feature of the acute inflammatory activation of macrophages.In this study, the effects of IL- …

… Next, to clarify the role of NF-κB in the wound healing migration of IL-28A… NF-κB subunits,
using a siRNA knockdown system. The NF-κB subunit p65 expression was inhibited in si-NFκB …

… Collectively, our results demonstrated that p38 MAPK signaling by IL-28A participated in
MMP-9 expression by activating NF-κB and AP-1 binding resulting in the degradation of ECM …

… , IL-8 promoter activity, and AP-1 nuclear extract binding but not NF-κB DNA binding. Our
data demonstrate that AP-1 and NF-κB are essential transcription factors for IL-1β-induced IL-8 …

… Using highly sensitive and quantitative detection systems, we only detected IL-28A in
monocytic cell populations if a certain expression level of IL-29 and IFN-β was reached [61], …

… Interleukin (IL)-29 is a new member of the recently discovered interferon (IFN) λ family,
together withIL-28A and IL-28B, comprising the Type III IFNs, also labeled as IFNλ1, IFNλ2 and …

… Accumulating results lead us to assume that interleukin (IL)-28 and IL-29, 2 novel members
of the IL-10-interferon cytokine family, are important regulators of some of these processes. …

… regulated by functional ISRE and NF-κB promoter elements. … features and antiviral activity
of IL-28A/B and IL-29 in other … IL-29 (and likely IL-28A/B) significantly contributes to the host …

… IL-28B primers/probe were designed based on human interleukin-28B (IFN-λ3), IL-28A (IFN-λ2),
and IL-29 (IFN-λ1) messenger RNA (mRNA) sequences using Primer3 Input (version 0.4…

… The plasma levels of IL-28A and IL-29 are significantly higher in RA patients than in healthy
people [… IL-29 and IL-28A in the peripheral blood of RA patients can attract monocytes [126]. …