[HTML][HTML] Programmed cell death-1 rs11568821 and interleukin-28B rs12979860 polymorphisms in autoimmune hepatitis

NK Gatselis, K Azariadis, A Lyberopoulou… - Journal of Translational …, 2021 - Elsevier
… Abbreviations are same as in the text: SNP, single nucleotide polymorphism; PD1, programmed
cell death-1; IL28B, interleukin 28B.*The position of the SNP alleles in sequence of each …

Interleukin-28B acts synergistically with cisplatin to suppress the growth of head and neck squamous cell carcinoma

K Yoshimoto, T Kishida, H Nakano… - Journal of …, 2011 - journals.lww.com
interleukin (IL)-28B administration moderately suppressed the growth of head and neck
squamous cell carcinomas in vivo. Mice were subcutaneously inoculated with SCCVII cells (day …

Assessment of serum interleukin-28 as a biomarker to predict mortality in traumatic patients with sepsis

Y Yang, J Chen, C Yi, F Yang, M Tang, Z Li, X Bai - Cytokine, 2022 - Elsevier
… In the present study, our results indicated that the early serum IL-28A and IL-28B were
both significantly elevated in severe traumatic patients with sepsis on the day of admission. …

[HTML][HTML] IL-28B/IFN-λ3 drives granzyme B loading and significantly increases CTL killing activity in macaques

MP Morrow, J Yan, P Pankhong, DJ Shedlock… - Molecular Therapy, 2010 - cell.com
… more granzyme B-mediated cell death of peptide pulsed targets. These data suggest that
IFN-λ3 is a potent effector of the immune system with special emphasis on CD8 + T-…

Interleukin 28 is a potential therapeutic target for sepsis

Q Luo, Y Liu, S Liu, Y Yin, B Xu, J Cao - Clinical Immunology, 2019 - Elsevier
… In vitro studies have shown that recombinant mouse IL-28B reduced the … hepatocellular
carcinoma cell line, and inhibition of EMCV activity elicited by recombinant mouse IL-28B could …

[PDF][PDF] Introduction to the genetics and biology of interleukin28B

T Urban, MR Charlton, DB Goldstein - Hepatology, 2012 - Wiley Online Library
… Hepatic ISG expression is associated with genetic variation in interleukin 28B and the
outcome of IFN therapy for chronic hepatitis C. Gastroenterology 2010;139:499-509. 28. …

Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

MP Morrow, P Pankhong, DJ Laddy… - Blood, The Journal …, 2009 - ashpublications.org
death after a lethal influenza challenge. This study shows that IL-28B may act as an effective
adjuvant for cellular … describe the differential effects of IL-28B and IL-12 on Treg populations …

[HTML][HTML] Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer

JJ McGuire, JS Frieling, CH Lo, T Li… - Nature …, 2021 - nature.com
… However, the effects of bone-marrow derived MSCs on PCa cells are less explored. Here,
we report MSC-derived interleukin-28 (IL-28) triggers prostate cancer cell apoptosis via IL-28 …

Interleukin-28 and interleukin-29: novel regulators of skin biology

K Wolk, K Witte, R Sabat - Journal of Interferon & Cytokine …, 2010 - liebertpub.com
… IL-28A, IL-28B, and IL-29 share a common cellular receptor consisting of the cytokine
receptor … The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol 6(4):328–…

Interleukin-28B plays a therapeutic role on mouse U14 cervical cancer cells by down-regulating CD4+ CD25+ FoxP3+ Regulatory T cells in vivo

X Chen, B Zhu, Y Luo, D Zhang, L Zhang… - International Journal of …, 2015 - ijgc.bmj.com
… with an epidermal growth factor receptor mutation, treated with IFN-L2 underwent growth
suppression and apoptotic cells death by STAT1 phosphorylation.In addition to the JAK/STAT …