Intermediate-risk acute myeloid leukemia therapy: current and future

K Döhner, P Paschka - Hematology 2014, the American Society …, 2014 - ashpublications.org
… management of patients with acute myeloid leukemia (AML). These chromosomal abnormalities
have been used to categorize patients into 3 risk groups: favorable, intermediate, and …

A focus on intermediate-risk acute myeloid leukemia: sub-classification updates and therapeutic challenges

H Awada, MK Mustafa Ali, B Thapa, H Awada… - Cancers, 2022 - mdpi.com
… -risk, and 53% of intermediate-risk AML patients per ELN … therapy choices in intermediate-risk
AML patients. For instance… were used for risk classification, intermediate-risk patients were …

Risk stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and gene expression markers

V Rockova, S Abbas, BJ Wouters… - Blood, The Journal …, 2011 - ashpublications.org
… Univariable survival analysis (Table 2) indicated inferior OS in intermediate-risk AML patients
with FLT3 ITD mutations (hazard ratio [HR] = 1.41; P = .017), whereas CEBPA DM (OS: HR …

TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics

WC Chou, SC Chou, CY Liu, CY Chen… - Blood, The Journal …, 2011 - ashpublications.org
… factor in patients with intermediate-risk cytogenetics, and its … separate AML patients with
intermediate-risk cytogenetics into … prognosis in AML patients with intermediate-risk cytogenetics, …

Association between measurable residual disease in patients with intermediate-risk acute myeloid leukemia and first remission, treatment, and outcomes

S Yu, Z Fan, L Ma, Y Wang, F Huang… - JAMA Network …, 2021 - jamanetwork.com
… 549 younger patients (aged 14-60 years) with intermediate-risk acute myeloid leukemia,
154 … postremission treatment for patients with intermediate-risk acute myeloid leukemia. …

Allogeneic hematopoietic cell transplantation vs standard consolidation chemotherapy in patients with intermediate-risk acute myeloid leukemia: a randomized clinical …

M Bornhäuser, C Schliemann, J Schetelig… - JAMA …, 2023 - jamanetwork.com
… confined to the 96 patients at intermediate risk according to the European Leukemia Network
classification. Most importantly, all 41 patients relapsing after consolidation chemotherapy (…

[HTML][HTML] Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing

B Wang, Y Liu, G Hou, L Wang, N Lv, Y Xu, Y Xu… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… For those with intermediate-risk cytogenetics, studies showed that auto-HSCT may …
stratification to the patients [45, 46]. In our study, five patients with intermediate molecular genotypes …

Myeloablative haploidentical transplantation is superior to chemotherapy for patients with intermediate-risk acute myelogenous leukemia in first complete remission

M Lv, Y Wang, YJ Chang, XH Zhang, LP Xu… - Clinical Cancer …, 2019 - AACR
… Acute myeloid leukemia with intermediate risk (cytogenetic and molecular; int-risk AML) …
The results of this trial will help answer the question of whether patients with int-risk AML …

Allogeneic hematopoietic stem cells transplantation improves the survival of intermediate-risk acute myeloid leukemia patients aged less than 60 years

Y Zhang, Y Zhang, Q Chen, G Tang, W Zhang… - Annals of …, 2019 - Springer
… in 223 patients under the age of 60 years old with intermediate-risk AML in CR1. Patients
) obtained improved overall survival (OS) than patients who treated with chemotherapy (5-year …

Acute myeloid leukemia outcome: role of nucleotide excision repair polymorphisms in intermediate risk patients

SS Strom, E Estey, UM Outschoorn… - Leukemia & …, 2010 - Taylor & Francis
intermediate cytogenetics. Because prognosis varies most widely among patients with
intermediate … The non-diploid intermediate group included patients with chromosomal aberrations …