International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2001 - ASPET
Four adenosine receptors have been cloned and characterized from several mammalian …
The receptors are named adenosine A 1 , A 2A , A 2B , and A 3 . The A 2A and A 2B receptors

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors—an update

BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2011 - ASPET
International Union of Basic and Clinical Pharmacology report on the nomenclature and
classification of adenosine receptors… The fact that the structure of one of the adenosine receptors

International union of basic and clinical pharmacology. CXII: adenosine receptors: a further update

AP IJzerman, KA Jacobson, CE Müller… - Pharmacological …, 2022 - ASPET
Our previous International Union of Basic and Clinical Pharmacology report on the
nomenclature and classification of adenosine receptors (2011) contained a number of emerging …

Introduction to adenosine receptors as therapeutic targets

KA Jacobson - Adenosine receptors in health and disease, 2009 - Springer
Adenosine acts as a cytoprotective modulator in response to … subtypes of G protein-coupled
adenosine receptors (ARs): A … lasting in the body than adenosine, have potential therapeutic …

Adenosine receptors: expression, function and regulation

S Sheth, R Brito, D Mukherjea, LP Rybak… - International journal of …, 2014 - mdpi.com
… The A 1 and A 2A AR possess high affinity for adenosine while the A 2B and A 3 AR show
relatively lower affinity for adenosine receptors [5]. These receptors belong to the superfamily …

Adenosine receptors in health and disease

S Gessi, S Merighi, K Varani, PA Borea - Advances in pharmacology, 2011 - Elsevier
… molecular characterization of adenosine receptors, which have … be speculated that adenosine
A 1 , A 2A , A 2B , and A 3 receptor-… of adenosine receptors’ role in health and disease. …

Adenosine receptor targeting in health and disease

S Gessi, S Merighi, D Fazzi, A Stefanelli… - Expert opinion on …, 2011 - Taylor & Francis
… these receptors in clinical development. Expert opinion: Selective ligands of A 1 , A 2A , A 2B
and A 3 adenosine receptors … the role of these adenosine receptors in health and disease. …

Adenosine receptor heteromers and their integrative role in striatal function

S Ferré, F Ciruela, C Quiroz, R Luján… - The Scientific World …, 2007 - Wiley Online Library
… By analyzing the functional role of adenosine receptor heteromers, … receptors cannot be
considered as single functional units anymore. Heteromerization of neurotransmitter receptors

[HTML][HTML] Adenosine receptors as drug targets—what are the challenges?

JF Chen, HK Eltzschig, BB Fredholm - Nature reviews Drug discovery, 2013 - nature.com
… decades that extracellular adenosine is an important … adenosine receptor agonists or
antagonists. Experimental studies have clarified the biological functions of four adenosine receptors

Emerging adenosine receptor agonists

ZG Gao, KA Jacobson - Expert opinion on emerging drugs, 2007 - Taylor & Francis
… Structures of adenosine receptor agonists in clinical trials for various conditions * . … of
selected agonists in clinical trials at four subtypes of adenosine receptors (EC 50 and K i , nM). …