… Using a replication-deficient adenovirus to transfer the cDNA of tumor necrosis factor-α to rat
lung… overexpression resulted in severe pulmonary inflammation with significant increases in …

… that causes few lung effects when inhaled alone can potentiate ozone toxicity, particularly
in the vicinity of the alveolar duct, where the accumulation of interstitial inflammatory cells may …

… In particular, it has been shown that intratracheal instillation of silica (50 mg/kg) in rats led
to fibrosis characterized by cellular interstitial infiltrates with granulomas, and in AM, it led to 1) …

… the onset of pulmonary inflammation and increased TGF-β1 lung tissue expression levels …
was decreased in cadmium chloride and TGF-β1 treated rat lung. Xiao et al. [6] demonstrated …

… a clear association with neutrophils and several inflammation markers especially TNF-α. …
44 Overexpression of TNF-α in the rat lungs led to severe pulmonary inflammation followed by …

… induced interstitial lung disease (DIILD). We aim to characterize a model of DIILD in the rat
and … All slices (0–16 sections) of one rat lung in the transverse plane starting from the superior …

… Rat lungs 7 days after instillation with FITC were stained with monoclonal anti-CD4 and
anti-CD8 and are illustrated in figs 3a and 3b. Of the lymphocytes, more than 95 per cent were …

… between the density of interstitial inflammation measured by these … interstitial inflammation
was expressed as the number of inflammatory cells (neutrophils and lympocytes) in the lung …

… fourpoint scoring system for each of the following: interstitial inflammation, interstitial fibrosis,
intraalveolar inflammation, type II epithelial cell hyperplasia, bronchiolization of alveoli, loss …

… hydroxyproline in lung and by grading of histopathology in trichrome-stained lung sections.
… in asbestos-exposed rat lungs and inhibition of this effect (p<0.05) in rats receiving the …