Klebsiella pneumoniae translocates across the intestinal epithelium via Rho GTPase-and phosphatidylinositol 3-kinase/Akt-dependent cell invasion

CR Hsu, YJ Pan, JY Liu, CT Chen, TL Lin… - Infection and …, 2015 - Am Soc Microbiol
… In this study, we investigated interactions between intestinal epithelial cells and clinical K.
pneumoniae strains that cause systemic infections. We used human intestinal cells to identify K

[HTML][HTML] Klebsiella pneumoniae induces inflammatory bowel disease through caspase-11–mediated IL18 in the gut epithelial cells

Q Zhang, X Su, C Zhang, W Chen, Y Wang… - Cellular and Molecular …, 2023 - Elsevier
Klebsiella pneumoniae J (KLPJ), from the colon tissues of patients with colitis. This strain of
bacteria could induce the production of mature IL18 in colon epithelial cells and gutcolon

Role of Lung Epithelial Cells in Defense against Klebsiella pneumoniae Pneumonia

G Cortés, D Álvarez, C Saus, S Albertí - Infection and immunity, 2002 - Am Soc Microbiol
… cells induces apoptosis, as occurs with other pathogens that invade intestinal epithelial
cells (17), and promotes the elimination of infected cells from the airway epithelium via cellular …

[HTML][HTML] Klebsiella pneumoniae activates the TGF-β signaling pathway to adhere to and invade intestinal epithelial cells via enhancing TLL1 expression

J Liu, S Zhang, H Pei, F Tu, B Liu, J Yan… - International Journal of …, 2022 - Elsevier
pneumoniae strains were used to infect intestinal epithelial Caco-2 cells to study the … TLL1
participates in K. pneumoniae adhesion and invasion of intestinal epithelial cells by activating …

Consequences of Reduction of Klebsiella pneumoniae Capsule Expression on Interactions of This Bacterium with Epithelial Cells

S Favre-Bonte, B Joly, C Forestier - Infection and immunity, 1999 - Am Soc Microbiol
… The presence of a capsule was shown to reduce the adhesion of enterotoxigenic Escherichia
coli to pig intestinal epithelial cells (27) and ofNeisseria meningitidis to both mucosal and …

A Novel Role for the Klebsiella pneumoniae Sap (Sensitivity to Antimicrobial Peptides) Transporter in Intestinal Cell Interactions, Innate Immune Responses, Liver …

CR Hsu, IW Chang, PF Hsieh, TL Lin… - The Journal of …, 2019 - academic.oup.com
pneumoniae infections may be preceded by gastrointestinal colonization, but the basis of …
’s interaction with the intestinal epithelium remains unclear. Here, we report that the K. …

Invasion of cultured human epithelial cells by Klebsiella pneumoniae isolated from the urinary tract

TA Oelschlaeger, BD Tall - Infection and immunity, 1997 - Am Soc Microbiol
… Human embryonic intestinal epithelial INT407 cells were grown in minimal essential medium
containing 10% FBS, 2 mM glutamine, and 0.1 mM nonessential amino acids. Cells were …

Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver

…, R Tanaka, J Matsuzaki, H Suzuki, K Hozumi - PLoS …, 2023 - journals.plos.org
intestinal mucosa decreases with age, allowing K. pneumoniae to readily invade the intestinal
epitheliumintestinal epithelium is essential for maintaining the intestinal mucosal barrier. …

Capsule Impedes Adhesion to and Invasion of Epithelial Cells by Klebsiella pneumoniae

H Sahly, R Podschun, TA Oelschlaeger… - Infection and …, 2000 - Am Soc Microbiol
… Human bladder epithelial cell line T24, human ileocecal epithelial cell line HCT-8, and
embryonic intestinal epithelial cell line INT 407 were cultivated as described by Oelschlaeger and …

Pathogenic potential of environmental Klebsiella pneumoniae isolates

C Struve, KA Krogfelt - Environmental microbiology, 2004 - Wiley Online Library
… Infections are frequently preceded by gastrointestinal colonization, and the gastrointestinal
… strains, our results reveal that, with respect to adhesion to and invasion of epithelial cells, K. …