Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
… the intranasal oxytocin administration route, suggesting that direct nose-to-brain delivery
underlies the behavioral effects of oxytocin on … intranasal oxytocin into psychiatric applications. …

Intranasal oxytocin: myths and delusions

G Leng, M Ludwig - Biological psychiatry, 2016 - Elsevier
… of intranasal oxytocin … of intranasal oxytocin also need proper dose-response studies, and
such studies need to include control subjects for peripheral effects, by administering oxytocin

Oxytocin plasma concentrations after single intranasal oxytocin administration–a study in healthy men

A Gossen, A Hahn, L Westphal, S Prinz, RT Schultz… - Neuropeptides, 2012 - Elsevier
… 210 min after oxytocin administration. Our data confirms previous findings that oxytocin
administered as a nasal spray enters the blood circulation, elevating oxytocin plasma levels for a …

Intranasal oxytocin administration is reflected in human saliva

O Weisman, O Zagoory-Sharon, R Feldman - Psychoneuroendocrinology, 2012 - Elsevier
… Following the discovery that intranasal administration of neuropeptides can reach the central
nervous system, a growing number of studies applied intranasal oxytocin (OT) paradigms …

Intranasal administration of oxytocin: behavioral and clinical effects, a review

JG Veening, B Olivier - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The intranasal (IN-) administration of substances is attracting attention from scientists as well
as pharmaceutical companies. The effects are surprisingly fast and specific. The present …

The impact of a single administration of intranasal oxytocin on the recognition of basic emotions in humans: a meta-analysis

S Shahrestani, AH Kemp, AJ Guastella - Neuropsychopharmacology, 2013 - nature.com
… Finally, if these tests are to provide reliable markers of response to oxytocin administration,
Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. …

Intranasal oxytocin administration attenuates the ACTH stress response in monkeys

KJ Parker, CL Buckmaster, AF Schatzberg… - …, 2005 - Elsevier
… This experiment investigated the effects of chronic intranasal OT administration on acute
stress-… were intranasally administered either 50μg oxytocin (N=6 monkeys) or 0μg oxytocin (N=6 …

A review of safety, side-effects and subjective reactions to intranasal oxytocin in human research

E MacDonald, MR Dadds, JL Brennan… - …, 2011 - Elsevier
administered intranasal oxytocin over a 13 week time period with daily administration of 40
IU placebo or oxytocin to … distributed between placebo and oxytocin. Nevertheless, there are …

Statistical and methodological considerations for the interpretation of intranasal oxytocin studies

H Walum, ID Waldman, LJ Young - Biological psychiatry, 2016 - Elsevier
… The effects sizes presented in the figure represent the largest (d = .48) and smallest (d = .21)
effects sizes within the field of intranasal oxytocin studies in humans, as well as the mean …

The acute effects of intranasal oxytocin administration on endocrine and sexual function in males

A Burri, M Heinrichs, M Schedlowski… - …, 2008 - Elsevier
… investigated the acute effects of intranasal OT application (24 IU) … OT plasma levels were
significantly elevated after intranasal OT … In conclusion, intranasally administered OT leads to a …