A randomized trial shows dose-frequency and genotype may determine the therapeutic efficacy of intranasal oxytocin
… whether efficacy may be influenced by dose frequency or genotype.MethodsIn a randomized…
5 days) intranasal oxytocin (24 international units) effects and oxytocin receptor genotype-…
5 days) intranasal oxytocin (24 international units) effects and oxytocin receptor genotype-…
Anxiolytic effects of chronic intranasal oxytocin on neural responses to threat are dose-frequency dependent
… dose frequency, and trait anxiety-specific effects, such that the low-frequency (intermittent)
chronic dosage … first evidence that low-dose frequency chronic intranasal OT has the potential …
chronic dosage … first evidence that low-dose frequency chronic intranasal OT has the potential …
[HTML][HTML] “Less is more”: a dose-response account of intranasal oxytocin pharmacodynamics in the human brain
D Martins, K Brodmann, M Veronese… - Progress in …, 2022 - Elsevier
… We further link physiological changes with the density of the oxytocin … intranasal oxytocin
as a valid approach to engage central targets. Finally, we demonstrate that intranasal oxytocin …
as a valid approach to engage central targets. Finally, we demonstrate that intranasal oxytocin …
A review of safety, side-effects and subjective reactions to intranasal oxytocin in human research
E MacDonald, MR Dadds, JL Brennan… - …, 2011 - Elsevier
… The total frequency of side-effects in this study was similar to studies involving the short-…
attention to the impact of intranasal oxytocin when applied in higher-dosage longer-term, when …
attention to the impact of intranasal oxytocin when applied in higher-dosage longer-term, when …
Intranasal oxytocin for negative symptoms of schizophrenia: systematic review, meta-analysis, and dose-response meta-analysis of randomized controlled trials
… frequency and compliance monitoring. We suggest that at least 1 more RCT with a high dose
of intranasal oxytocin … drawn about the effect of intranasal oxytocin on negative symptoms. …
of intranasal oxytocin … drawn about the effect of intranasal oxytocin on negative symptoms. …
Evidence for intranasal oxytocin delivery to the brain: recent advances and future perspectives
DS Quintana, KT Smerud, OA Andreassen… - Therapeutic …, 2018 - Taylor & Francis
… and neural effects of single-dose intranasal administration (8 and 24 IU doses), intravenous
… on the effect produced and on dose and, possibly, dosing frequency. If specific brain regions …
… on the effect produced and on dose and, possibly, dosing frequency. If specific brain regions …
[HTML][HTML] Effects of intranasal administration of oxytocin and vasopressin on social cognition and potential routes and mechanisms of action
S Yao, KM Kendrick - Pharmaceutics, 2022 - mdpi.com
… the importance of dose magnitude and frequency for influencing … functional effects of intranasal
oxytocin and vasopressin in … importance of dose magnitude and frequency for influencing …
oxytocin and vasopressin in … importance of dose magnitude and frequency for influencing …
Oxytocin and migraine headache
A Tzabazis, S Kori, J Mechanic, J Miller… - … : The Journal of …, 2017 - Wiley Online Library
… effects of one month of intranasal oxytocin dosing did show a … in both chronic and high
frequency episodic migraineurs. This … intranasal oxytocin on headache frequency we observed in …
frequency episodic migraineurs. This … intranasal oxytocin on headache frequency we observed in …
[HTML][HTML] Effects of multiple-dose intranasal oxytocin administration on social responsiveness in children with autism: a randomized, placebo-controlled trial
… both the oxytocin and placebo … intranasal oxytocin. Notably, in the single-blind phase,
participants who were first allocated to intranasal placebo and later changed to intranasal oxytocin …
participants who were first allocated to intranasal placebo and later changed to intranasal oxytocin …
Intranasal oxytocin, social cognition and neurodevelopmental disorders: a meta-analysis
B Keech, S Crowe, DR Hocking - Psychoneuroendocrinology, 2018 - Elsevier
… By considering the influence of diagnosis, age, dose of IN-OT, frequency of administration
and outcome measures on the results of these studies, the present study aimed to more …
and outcome measures on the results of these studies, the present study aimed to more …
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