Oxytocin Receptors on Calvarial Periosteal Innervation: Therapeutic Target for Post-Traumatic Headache?

VN Bharadwaj, M Klukinov, RP Cowan, N Mahinparvar… - Pharmaceutics, 2024 - mdpi.com
… are composed mainly of pain-sensing nerve fibers [10,13]. … —a marker for sensory pain nerve
fibers—have been reported … , the application of nasal oxytocin reduced PTH-related pain in …

Low-dose intranasal oxytocin delivered with Breath Powered device modulates pupil diameter and amygdala activity: a randomized controlled pupillometry and fMRI …

DS Quintana, LT Westlye, D Alnæs… - …, 2019 - nature.com
… 24IU intranasal oxytocin or 1IU intravenous oxytocinoxytocin is in line with the hypothesis
that intranasal oxytocin administration delivers oxytocin to the brain via nose-to-brain nerve

CSF and blood oxytocin concentration changes following intranasal delivery in macaque

O Dal Monte, PL Noble, J Turchi, A Cummins… - PloS one, 2014 - journals.plos.org
… We found that intranasal administration of exogenous OT increased … after nasal spray
compared to nebulizer. In conclusion our study provides evidence that both nebulizer and nasal

[HTML][HTML] Chemogenetic Activation of Oxytocin Neurons Improves Pain in a Reserpine-induced Fibromyalgia Rat Model

N Ikeda, M Kawasaki, K Baba, H Nishimura, T Fujitani… - Neuroscience, 2023 - Elsevier
… syndrome characterized by chronic pain with depression as … pain and depressive symptoms
of FM is lacking. Given that endogenous oxytocin (OXT) contributes to the regulation of pain

Sensory stimulation of oxytocin release is associated with stress management and maternal care

T Takahashi - Frontiers in Psychology, 2021 - frontiersin.org
Oxytocin (OT) is mainly produced in the supraoptic nucleus (SON) and paraventricular
nucleus (… Thus, oxytocin may reduce fear responses and increase social functioning in patients …

Pain, parental involvement, and oxytocin in the neonatal intensive care unit

M Filippa, P Poisbeau, J Mairesse, MG Monaci… - Frontiers in …, 2019 - frontiersin.org
Preterm infants (PTI) typically experience many painful and … period stimulate the oxytocin
system, reduce pain and stress, … a focus on the effects of pain, and early maternal separation. …

C-tactile afferents: Cutaneous mediators of oxytocin release during affiliative tactile interactions?

SC Walker, PD Trotter, WT Swaney, A Marshall… - Neuropeptides, 2017 - Elsevier
… and its associated inflammation, and neuropathic pain which is a maladaptive response to a
… that intranasal administration of oxytocin not only attenuates perceived pain intensity of the …

Phase 1 safety assessment of intrathecal oxytocin

JC Eisenach, C Tong, R Curry - Anesthesiology, 2015 - pubs.asahq.org
… and drug exposure should be greater to left nerve roots and spinal cord when the subject is
in … of 1,529 subjects receiving 18 to 72 μg intranasal oxytocin without the evidence of toxicity. …

Oxytocin Modulation in Mindfulness-Based Pain Management for Chronic Pain

O Aygün, E Mohr, C Duff, S Matthew, P Schoenberg - Life, 2024 - mdpi.com
… Management would dampen inflammation and stress biomarkers, while increasing oxytocin
pain symptomatology. Additionally, we hypothesized that oxytocin could be linked to pain

Prolactin and oxytocin

AK Szewczyk, S Ulutas, T Aktürk, L Al-Hassany… - 2023 - dadun.unav.edu
oxytocin should enhance its signalling and antinociceptive effects, for example using intranasal
administration of oxytocin… trigeminal nerve-associated pain responses in vivo. Moreover, …