Effects of intranasal oxytocin on pain perception among human subjects: A systematic literature review and meta-analysis

S Lopes, F de Lima Osório - Hormones and Behavior, 2023 - Elsevier
… effect of intranasal OXT administration on pain perception, … , being weak, may also not be
perceived at a conscious level. … of the painful condition, such as pain complexity, intensity, and …

Oxytocin and pain perception: from animal models to human research

S Boll, ACA De Minas, A Raftogianni, SC Herpertz… - Neuroscience, 2018 - Elsevier
… evaluated studies reported OT effects on certain aspects of pain perception only. The
intranasal administration of OT did not reduce ischemic pain sensitivity, but resulted in enhanced …

Sex-specific effects of intranasal oxytocin on thermal pain perception: a randomised, double-blind, placebo-controlled cross-over study

LM Tracy, I Labuschagne… - …, 2017 - Elsevier
oxytocin has been implicated as a potential therapeutic for the management of chronic pain
… This study investigated the influence of intranasal oxytocin on the perception of noxious …

Effects of intranasal oxytocin on thermal pain in healthy men: a randomized functional magnetic resonance imaging study

M Zunhammer, S Geis, V Busch… - Psychosomatic …, 2015 - journals.lww.com
oxytocin as an adjunctive treatment of chronic pain is of considerable interest. Nevertheless,
the potential of intranasal oxytocin to affect pain … of oxytocin on experimental pain perception

Intranasal administration for pain: oxytocin and other polypeptides

VN Bharadwaj, AZ Tzabazis, M Klukinov, NA Manering… - Pharmaceutics, 2021 - mdpi.com
… Interestingly, sex-specific effects of intranasal oxytocin on pain perception have been …
Sex-specific effects of intranasal oxytocin on thermal pain perception, suggesting that oxytocin and …

[HTML][HTML] Oxytocin effects on pain perception and pain anticipation

SC Herpertz, MM Schmitgen, C Fuchs, C Roth… - … Journal of Pain, 2019 - Elsevier
… In a fear conditioning paradigm, intranasal … both pain perception and pain anticipation to
distinguish potential mechanisms underlying the effects of intranasally administered OT on pain. …

Pain modulation by intranasal oxytocin and emotional picture viewing—a randomized double-blind fMRI study

M Zunhammer, S Geis, V Busch, P Eichhammer… - Scientific reports, 2016 - nature.com
… dimension of pain. This randomized, placebo-controlled, double-blind, crossover study
explored whether intranasal oxytocin and emotional context can affect heat pain perception in 30 …

Intranasal oxytocin administration is associated with enhanced endogenous pain inhibition and reduced negative mood states

BR Goodin, AJB Anderson, EL Freeman… - … journal of pain, 2015 - journals.lww.com
… The third and last finding revealed from this study was that intranasal oxytocin was not
significantly associated with decreased ischemic pain sensitivity (ie, pain tolerance, ratings of pain

Intranasal oxytocin attenuates reactive and ongoing, chronic pain in a model of mild traumatic brain injury

AC Meidahl, A Eisenried, M Klukinov… - … Head and Face Pain, 2018 - Wiley Online Library
… transmission or modulation and all make potential targets for OT-mediated pain perception
modulation. More recently, OT has been shown to attenuate neuronal hyper excitability in the …

Evaluating the efficacy of intranasal oxytocin on pain and function among individuals who experience chronic pain: a protocol for a multisite, placebo-controlled …

JA Rash, TS Campbell, L Cooper, D Flusk… - BMJ open, 2021 - bmjopen.bmj.com
tolerance in 29 out of 33 animal studies reviewed. This effect was large (standard mean
difference=2.28), and persisted across central and peripheral modes of administration and …