… studies and intrathecal chemotherapy increases the median … with radiation and intrathecal
methotrexate. As currently … and subsequently with intrathecal chemotherapy, markedly …

… Intrathecal chemotherapy Intrathecal chemotherapy has been the mainstay of treatment
for leptomeningeal metastasis. Drug can be delivered either by lumbar puncture or via an in…

… , whereas those with a positive CSF cytology but negative imaging may be treated with
intrathecal chemotherapy and spared the systemic toxicity of intravenous drug. Despite vigorous …

… chemotherapy, intrathecal chemotherapy and radiotherapy of cerebral and of spinal
leptomeninges… of the fact that in case of CNS metastases the performance status is a very …

… Leptomeningeal metastasis (LM) is increasingly common in patients with non‑small cell …
The current study is a pooled analysis that evaluated intrathecal chemotherapy (ITC) as a …

… Intrathecal chemotherapy is most important in cases of LM of the non-adherent type. There
are three substances for routine use for intrathecal chemotherapy: methotrexate, cytarabine, …

… treatment for leptomeningeal carcinomatosis. Using case … of IT chemotherapy in treating
leptomeningeal carcinomatosis. … to compare hormone therapy, chemotherapy, and IT therapy. …

… infiltration of leptomeninges by malignant … intrathecal chemotherapy (ITC) to patients having
solid tumors with cerebrospinal fluid (CSF) cytology positive leptomeningeal carcinomatosis. …

… A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt)
to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors. Clin …

… of intrathecal methotrexate plus dexamethasone and concomitant involved field radiotherapy
has been explored in a phase II trial in patients with leptomeningeal metastases from …