Intrauterine environment and polycystic ovary syndrome

DA Dumesic, MO Goodarzi… - Seminars in …, 2014 - thieme-connect.com
environments. The latter is particularly relevant when considering that adverse intrauterine
environments … would be exposed to the same intrauterine environment. Thus, fetal androgen …

[HTML][HTML] Fetal programming of polycystic ovary syndrome

EB Gur, M Karadeniz, GA Turan - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
… In this review, the possible roles of intrauterine environmental … , an insufficient intrauterine
nutritional environment may also … environment and to the intrauterine nutritional environment. …

Which origin for polycystic ovaries syndrome: genetic, environmental or both?

P Fenichel, C Rougier, S Hieronimus… - Annales d' …, 2017 - Elsevier
… programming by impairment of the foetal environment. In fact, the metabolic syndrome and
PCOS, which share some elements, may have an intrauterine origin and become part of adult …

Impact of intra-uterine life on future health

L Azoulay, C Bouvattier, S Christin-Maitre - Annales d'Endocrinologie, 2022 - Elsevier
polycystic ovary syndrome (PCOS) in mice. In summary, an increasing number of examples
of the impact of intrauterine … greater vulnerability of male fetuses to environmental pollutants. …

Genetic and environmental factors in the etiology of polycystic ovary syndrome

TM Barber, S Franks - The Ovary, 2019 - Elsevier
… These observations suggest that intrauterine environmental … states that the intrauterine
environment is contributory to … to occur: (i) intrauterine nutritional restriction results in changes to …

Understanding the pathogenesis of polycystic ovary syndrome: transgenerational evolutionary adaptation to lifestyle and the environment

J Parker - … Australasian College of Nutritional and Environmental …, 2020 - search.informit.org
… genetic and environmental factors involved in the pathogenesis of polycystic ovary syndrome
(… it would further support the notion of intrauterine developmental programming in PCOS. …

Pathophysiology of polycystic ovary syndrome revisited: Current understanding and perspectives regarding future research

M Harada - Reproductive medicine and biology, 2022 - Wiley Online Library
… factors mentioned above in the pathogenesis of PCOS, namely, local ER stress in the follicular
microenvironment and the androgen-rich intrauterine environment of mothers with PCOS, …

Intrauterine reprogramming of the polycystic ovary syndrome: evidence from a pilot study of cord blood global methylation analysis

L Lambertini, SR Saul, AB Copperman… - Frontiers in …, 2017 - frontiersin.org
… an intrauterine epigenetic … intrauterine environment exposure exists, we hypothesized that
PCOS during pregnancy induces fetal epigenetic reprogramming resulting from intrauterine

[PDF][PDF] Polycystic ovary syndrome: the influence of environmental and genetic factors

E Diamanti-Kandarakis, C Piperi… - HORMONES …, 2006 - academia.edu
… in intrauterine life. Obese, hirsute women with polycystic ovaries have higher than normal
ovarian … Lean women with polycystic ovaries have altered hypothalamic control of LH release …

Epigenetic abnormality: a possible mechanism underlying the fetal origin of polycystic ovary syndrome

Z Li, H Huang - Medical hypotheses, 2008 - Elsevier
… early in development, and particularly during intrauterine life, can lead to the permanent …
has been accepted that abnormal intrauterine environment may ultimately lead to abnormal …