Intravenous artesunate for the treatment of severe malaria

KM Hess, JA Goad, PM Arguin - Annals of Pharmacotherapy, 2010 - journals.sagepub.com
… Health Organization's malaria treatment guidelines. While there are no published head-to-head
trials of intravenous artesunate versus intravenous quinidine for severe malaria, several …

[HTML][HTML] Intravenous artesunate for severe malaria in travelers, Europe

T Zoller, T Junghanss, A Kapaun, I Gjørup… - Emerging infectious …, 2011 - ncbi.nlm.nih.gov
… caused by severe malaria (14). We report data for 25 patients with severe malaria who were
treated with IV artesunate in 7 treatment centers in areas to which malaria was not endemic. …

[HTML][HTML] Artesunate: the best drug in the treatment of severe and complicated malaria

Q Li, P Weina - Pharmaceuticals, 2010 - mdpi.com
… This review summarizes progress in treating severe and complicated malaria, which are …
pathogenesis of severe malaria complications. New drugs such as intravenous artesunate (AS) …

[HTML][HTML] Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium

AR Kreeftmeijer-Vegter, PJ van Genderen, LG Visser… - Malaria journal, 2012 - Springer
… case series of patients with severe malaria in Europe. Mortality … travellers with severe malaria
treated with IV artesunate [7]. … before; IV artesunate is an excellent drug for severe malaria, …

A simplified intravenous artesunate regimen for severe malaria

PG Kremsner, T Taylor, S Issifou… - Journal of Infectious …, 2012 - academic.oup.com
… reduce mortality of children with severe malaria in a similar comparison with … intravenous
artesunate would be as efficacious in clearing peripheral parasitemia as the more complicated 5…

Artesunate to treat severe malaria in travellers: review of efficacy and safety and practical implications

C Roussel, E Caumes, M Thellier… - Journal of travel …, 2017 - academic.oup.com
… In 2010, WHO has introduced the clear recommendations of using intravenous (IV) AS in
all patients with severe malaria—adults, children and pregnant women—including those …

[HTML][HTML] Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults

P Byakika-Kibwika, M Lamorde, J Mayito, L Nabukeera… - Malaria journal, 2012 - Springer
… of intravenous artesunate for treatment of severe malaria. Previous studies have
demonstrated superiority of intravenous artesunate over intravenous quinine for severe malaria

Intravenous artesunate for the treatment of severe and complicated malaria in the United States: clinical use under an investigational new drug protocol

PS Twomey, BL Smith, C McDermott… - Annals of internal …, 2015 - acpjournals.org
… To assess the safety, tolerability, and clinical benefit of intravenous artesunate among US
patients with severe and complicated malaria, we evaluated medical records for patients …

[HTML][HTML] Severe malaria and artesunate treatment, Norway

K Mørch, Ø Strand, O Dunlop, Å Berg… - Emerging infectious …, 2008 - ncbi.nlm.nih.gov
… In conclusion, the current case series suggests that IV artesunate is an efficacious and
safe treatment option in travelers returning from West Africa with severe falciparum malaria. …

Pharmacokinetics and pharmacodynamics of intravenous artesunate in severe falciparum malaria

TME Davis, HL Phuong, KF Ilett, NC Hung… - Antimicrobial agents …, 2001 - Am Soc Microbiol
… derivatives in severe malaria, we studied 30 Vietnamese adults with slide-positive
falciparum malaria treated with intravenous artesunate. Twelve patients with complications (severe; …