… In many cases, however, activation of the Raf/MEK/ERK pathway alone is … PI3K/Akt pathway
is a viable target for novel antineoplastic drugs. This review will describe PI3K/Akt pathway …

… by PI3K/Akt, hence this pathway may decisively contribute to the resistant phenotype. Many
of the signalling pathways involved in … The PI3K/Akt pathway is involved in many of the …

… hypoxia, the PI3K, AKT and MAPK pathways mediate primarily non-hypoxic HIF regulation.
Here we will focus primarily on pathways that lead to HIF activation via PI3K/AKT, and mTOR/…

… When talking about PI3K/AKT pathway, we have to mention phosphatase and … PI3K/AKT
pathway. As a lipid phosphatase, PTEN directly suppresses the activation of PI3K/AKT pathway …

… HGF is most involved in promoting migration. … The present study demonstrated that activation
of the PI3K/Akt pathway induced by the HGF/c-Met axis was involved in the downregulation …

… Based on these data, we hypothesize that the hyperactivation PI3K/AKT pathway in psoriatic
lesions could be implicated in the regulation of the senescent-like phenotype of epidermal …

… reversed by a PI3K/Akt inhibitor (wortmannin). Our in vitro and in vivo results suggested that
activation of the PI3K/Akt pathway and the inhibition of NF-κB were involved in the protective …

… In this review, we underline the involvement of this pathway in patho-physiological cell
survival mechanisms, emphasizing its key role in the development of drug resistance. We also …

… Two signaling pathways, phosphatidylinositol 3-kinase (PI3K)/Akt to target of rapamycin (…
involved in muscle hypertrophy. In this study we examined the involvement of these pathways …

… demonstrates PI3K/PTEN/AKT/mTOR signaling pathway is … PI3K/PTEN/AKT/mTOR
signaling pathway is involved in … Therefore, PI3K/PTEN/AKT/mTOR pathway could serve as a …