Solving ion channel kinetics with the QuB software

C Nicolai, F Sachs - Biophysical Reviews and Letters, 2013 - World Scientific
ion channels led to the need to extract the underlying kinetic … The software is open source
and, in addition to solving kinetic … QuB also can analyze the kinetics of multichannel data …

Memory in ion channel kinetics

MP Silva, CG Rodrigues, WA Varanda, RA Nogueira - Acta Biotheoretica, 2021 - Springer
Ion channels are transport proteins present in the lipid bilayers of biological membranes. They
are involved in many physiological processes, such as the generation of nerve impulses, …

Fractal model of ion-channel kinetics

LS Liebovitch, J Fischbarg, JP Koniarek… - … et Biophysica Acta (BBA …, 1987 - Elsevier
… If such a fractal scaling also applies to the current flow through an ion channel, then as we
observe the current at higher frequency resolution we will observe the channel fluctuating …

Ion channel kinetics

LS Liebovitch, JP Koniarek - IEEE Engineering in Medicine and …, 1992 - ieeexplore.ieee.org
… However, processes also have fractal propered ion channels, for exin the lipid bilayer that
forms the … help us to understand the physical attributes of the ion channel protein. on Channels

Simulating complex ion channel kinetics with IonChannelLab

JA De Santiago-Castillo, M Covarrubias… - Channels, 2010 - Taylor & Francis
… , can be used to simulate gating kinetics of ion channels. Also, more … programs for kinetic
simulation of ion channels are more … Because we consider that a successful program for kinetic

The physical basis of ion channel kinetics: the importance of dynamics

LS Liebovitch, P Krekora - IMA Volumes in Mathematics and its …, 2002 - books.google.com
… Ions cross the cell membrane through ion channel proteins. The traditional approaches
have analyzed channel proteins as if they existed in a few stable conformations and switched …

Fractal methods to analyze ion channel kinetics

LS Liebovitch, D Scheurle, M Rusek, M Zochowski - Methods, 2001 - Elsevier
… the currents through ion channels in ways of thinking about scientific problems that he …
through the channel protein. During the times ion channels assumed that channel proteins have a …

Ion channel kinetics: a model based on fractal scaling rather than multistate Markov processes

LS Liebovitch, J Fischbarg, JP Koniarek - Mathematical Biosciences, 1987 - Elsevier
… of ion channel kinetics, the kinetic rate constants increase as we measure the current through
the channel … That is, the faster we can look, the faster we see the channel fluctuating open …

[HTML][HTML] Maximum likelihood estimation of ion channel kinetics from macroscopic currents

LS Milescu, G Akk, F Sachs - Biophysical journal, 2005 - cell.com
… We review here some basic results of ion channel kinetics, for an arbitrary Markov model
with N S conformational states. Rate constants are conventionally expressed as an N S × N S …

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

W Dalemans, P Barbry, G Champigny, S Jallat, S Jallat… - Nature, 1991 - nature.com
… AF508 CFTR expression induced a reduced activity of the cAMPactivated CIT channel,
with conductance, anion selectivity and open-time kinetics similar to those of CFTR, but with …