Activating macrophages for enhanced osteogenic and bactericidal performance by Cu ion release from micro/nano-topographical coating on a titanium substrate

Q Huang, Z Ouyang, Y Tan, H Wu, Y Liu - Acta biomaterialia, 2019 - Elsevier
macrophages is extracellular. So far, the mechanisms of extracellular Cu ions on macrophage
polarization and macrophage-… ions released from biomaterials on macrophage response. …

Ion channels in microglia (brain macrophages)

C Eder - American Journal of Physiology-Cell Physiology, 1998 - journals.physiology.org
… inhibition after G protein activation has been described for other macrophage preparations
(96, … It has been demonstrated that activation of macrophages with LPS or interferon-γ (IFN-γ) …

Sustained calcium ion release from bioceramics promotes CaSR-mediated M2 macrophage polarization for osteoinduction

J Zhang, Q Wu, C Yin, X Jia, Z Zhao… - Journal of leukocyte …, 2021 - academic.oup.com
… This study found that BCP could slowly and continuously release Ca 2+ ions and
enhance M2 macrophage polarization, activating the continuous high expression of Wnt/β-catenin …

Titanium ions form particles that activate and execute interleukin‐1β release from lipopolysaccharide‐primed macrophages

M Pettersson, P Kelk, GN Belibasakis… - Journal of …, 2017 - Wiley Online Library
activation and IL-1β secretion in macrophages. We show that Ti ions form particles in a
physiological solution and induce a proinflammatory reaction in human macrophages in vitro. In …

Platelet activating factor raises intracellular calcium ion concentration in macrophages.

GW Conrad, TJ Rink - The Journal of cell biology, 1986 - rupress.org
… 2+ influx and internal release in platelets have analogous effects on macrophages, raising
[… receptors for PAF exist on the surfaces of macrophages, as they appear on platelets and on …

Macrophage polarization and activation in response to implant debris: influence by" particle disease" and" ion disease"

YT Konttinen, J Pajarinen, Y Takakubo… - Journal of long-term …, 2014 - dl.begellhouse.com
… gamma-interferon activating factor GAF to the nucleus, where it binds to gamma activated
site GAS initiating transcription. Primed macrophages are not activated but they are tuned to …

Regulation of immune response by bioactive ions released from silicate bioceramics for bone regeneration

Y Huang, C Wu, X Zhang, J Chang, K Dai - Acta biomaterialia, 2018 - Elsevier
… due to the apoptosis of macrophages induced by the bioactive ions released by silicate
bioceramics. … Our results showed the activation of all of caspase-9, 8 and 3 in RAW264.7, which …

[HTML][HTML] Effective actions of ion release from mesoporous bioactive glass and macrophage mediators on the differentiation of osteoprogenitor and endothelial …

A Polo-Montalvo, L Casarrubios, MC Serrano… - Pharmaceutics, 2021 - mdpi.com
… (EPC RAW); this demonstrates the sensitivity of this experimental coculture model and shows
the different effect of macrophages, depending on their phenotype and activation state [23,…

Regulation of macrophage activation

J Ma, T Chen, J Mandelin, A Ceponis, NE Miller… - Cellular and Molecular …, 2003 - Springer
… , size, shape, rigidity, charge and chemical structure have been considered important for
macrophage activation. Implant metal ions (Co, Cr) enhance cytokine release from activated

[HTML][HTML] The contribution of ion channels to shaping macrophage behaviour

A Selezneva, AJ Gibb, D Willis - Frontiers in Pharmacology, 2022 - frontiersin.org
ion channel families in macrophage functions. Finally, we highlight some areas of ion channel
research in macrophages … Research on Ca 2+ -activated K + channel in macrophages has …