[HTML][HTML] N-glycosylation determines ionic permeability and desensitization of the TRPV1 capsaicin receptor
The balance of glycosylation and deglycosylation of ion … of glycosylation of the TRPV1 receptor,
a key sensor of pain-… of capsaicin-evoked desensitization and ionic permeability. Both N-…
a key sensor of pain-… of capsaicin-evoked desensitization and ionic permeability. Both N-…
[HTML][HTML] Mechanism of capsaicin receptor TRPV1-mediated toxicity in pain-sensing neurons focusing on the effects of Na+/Ca2+ fluxes and the Ca2+-binding protein …
L Pecze, W Blum, B Schwaller - … et Biophysica Acta (BBA)-Molecular Cell …, 2013 - Elsevier
… Ionic currents through TRPV1 channels are different at higher [Ca 2 + ] o : the reduction in the
ratio of Ca 2 + and Na + ion permeability (… more permeable to Na + ions than to Ca 2 + ions …
ratio of Ca 2 + and Na + ion permeability (… more permeable to Na + ions than to Ca 2 + ions …
Capsaicin binds to the intracellular domain of the capsaicin-activated ion channel
J Jung, SW Hwang, J Kwak, SY Lee… - Journal of …, 1999 - Soc Neuroscience
… expressing vanilloid receptor 1, a recently cloned CAP receptor. Hydrogen ions, reported as
a … Similar to the CAP-activated ion channel, the acid-sensitive ion channel is permeable to …
a … Similar to the CAP-activated ion channel, the acid-sensitive ion channel is permeable to …
Activity-dependent targeting of TRPV1 with a pore-permeating capsaicin analog
H Li, S Wang, AY Chuang… - Proceedings of the …, 2011 - National Acad Sciences
… The capsaicin receptor TRPV1 is the principal transduction … Given that relative permeability
of small metal ions for … of relative permeability of large organic cations (16). Such dynamic …
of small metal ions for … of relative permeability of large organic cations (16). Such dynamic …
Mechanism of action of capsaicin-like molecules on sensory neurons
A Dray - Life sciences, 1992 - Elsevier
… The capsaicin-induced ion permeability changes have … ions. It is possible that desensitization
may involve affinity changes in the capsaicin receptor or an uncoupling of the receptor-ion …
may involve affinity changes in the capsaicin receptor or an uncoupling of the receptor-ion …
The capsaicin receptor: a heat-activated ion channel in the pain pathway
MJ Caterina, MA Schumacher, M Tominaga, TA Rosen… - Nature, 1997 - nature.com
… Given the high permeability of VR1 to calcium ions, we nonetheless considered the
possibility that it might function as a SOC. To test this, we examined calcium-dependent inward …
possibility that it might function as a SOC. To test this, we examined calcium-dependent inward …
Capsaicin receptor in the pain pathway
M Tominaga, D Julius - The Japanese Journal of Pharmacology, 2000 - jstage.jst.go.jp
… A similar topological structure has been reported for many ion … TRP (transient receptor
potential) family of ion channels (see … -activated currents showed non-selective cation permeability …
potential) family of ion channels (see … -activated currents showed non-selective cation permeability …
Pharmacology of the capsaicin receptor, transient receptor potential vanilloid type-1 ion channel
… of capsaicin and its receptor the transient receptor potential vanilloid type 1 ion channel (…
an account of our current knowledge of the pharmacology of the capsaicin receptor, TRPV1. …
an account of our current knowledge of the pharmacology of the capsaicin receptor, TRPV1. …
The ionic basis of capsaicin-evoked responses
S Bevan, RJ Docherty - Neurogenic Inflammation. CRC Press …, 1996 - books.google.com
… the ionic permeability of the conductance pathway. The reversal potential for the capsaicin-…
and RTX, 10 argue strongly for the existence of a specific capsaicin receptor. The activity of …
and RTX, 10 argue strongly for the existence of a specific capsaicin receptor. The activity of …
Integrating TRPV1 receptor function with capsaicin psychophysics
G Smutzer, RK Devassy - Advances in Pharmacological and …, 2016 - Wiley Online Library
… of the capsaicin receptor, Transient Receptor Potential … [16–19], a well characterized ion
channel that localizes to … rectifying cation channel that is permeable to both monovalent and …
channel that localizes to … rectifying cation channel that is permeable to both monovalent and …
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