… It has long been known that whole-body irradiation induces a … marrow cells, including depletion
of hematopoietic stem cells … cell-cycle response to irradiation in mesenchymal stem cells (…

… 1960s when Till and McCulloch discovered hematopoietic stem cells (HSCs) (15, … irradiated
animals. Till and McCulloch’s landmark discovery laid the foundation for modern stem cell …

… Effect of irradiation on expression of multipotent stem cell markers in hNSCs. Immunocytochemical
analyses of hNSCs show strong expression and colocalization of multipotent markers …

… We use RCS, ie the ratio of RG of irradiated cells to RG of sham-irradiated cells as a measure
of their radiosensitivity. We found that RCS varied between different hESC lines. The RCS …

… Mesenchymal stem cells (MSCs) are a type of bone marrow stem cell that possesses self-renewal
ability … After irradiating hMSCs according to the indicated irradiation schedule, viable …

… (red panel) upon irradiation with 10 Gy. (B) Relative expression patterns of positive and
negative stem cell surface marker genes of 2 MSC samples after ionizing irradiation treatment. …

… increased remarkably in cells of EB derived from nonirradiated iPS cells; however, in … cells,
especially iPS cells. Therefore, investigating whether iPS stem cells are sensitive to ionizing …

… of ionizing radiations on the hematopoietic stem cells, which are prone to long-term deleterious
effects. Impact of high doses of irradiation on hematopoietic cells … to irradiation and with a …

… mesenchymal stem cell line and subsequently irradiated this … ionizing radiation on these
cells and investigate whether radiation can trigger tumor development. The cells were irradiated …

… Here we report that ionizing radiation can induce stem cell-… irradiation of cancer cells as a
novel potential origin of cancer stemness. Exposure of heterogeneous cancer cells to ionizing …