… , which promote or inhibit intestinal iron absorption: making a platform for dietary measures that can reduce iron uptake in patients with genetic haemochromatosis
NT Milman - Journal of Nutrition and Metabolism, 2020 - Wiley Online Library
… with iron, but the net effect has not been clarified. Conclusions. In haemochromatosis, iron
absorption is … Dietary modifications that lower iron intake and decrease iron bioavailability may …
absorption is … Dietary modifications that lower iron intake and decrease iron bioavailability may …
Genetics of haemochromatosis
A Bomford - The Lancet, 2002 - thelancet.com
… Major questions also remain unanswered about the role of HFE, and other genes mutated
in haemochromatosis, in iron absorption and maintenance of homoeostasis of iron. The …
in haemochromatosis, in iron absorption and maintenance of homoeostasis of iron. The …
Haemochromatosis
P Brissot, A Pietrangelo, PC Adams… - Nature reviews Disease …, 2018 - nature.com
… definition excludes rare genetic disorders that lead to systemic iron excess by …
haemochromatosis in individuals homozygous for C282Y by decreasing iron absorption or …
haemochromatosis in individuals homozygous for C282Y by decreasing iron absorption or …
Haemochromatosis
A Pietrangelo - Gut, 2003 - gut.bmj.com
… haemochromatosis, increased iron absorption leads to dramatic expansion of the iron
stores while iron … becomes starved of iron leading to activation of the genetic iron import-export …
stores while iron … becomes starved of iron leading to activation of the genetic iron import-export …
Genetic haemochromatosis: genes and mutations associated with iron loading
C Camaschella, A Roetto, M De Gobbi - Best Practice & Research Clinical …, 2002 - Elsevier
… iron absorption, a proportion of haemochromatosis patients have wildtype HFE but have
mutations in other genes… , characterized by deregulation of iron absorption, may provide insights …
mutations in other genes… , characterized by deregulation of iron absorption, may provide insights …
Diagnosis and therapy of genetic haemochromatosis (review and 2017 update)
EJ Fitzsimons, JO Cullis, DW Thomas… - British Journal of …, 2018 - discovery.ucl.ac.uk
… of 30 years, is inherited in an autosomal recessive fashion and is characterised by excessive
iron absorption from the GI tract, excessive iron release from RES macrophages, excessive …
iron absorption from the GI tract, excessive iron release from RES macrophages, excessive …
Pathogenesis of genetic haemochromatosis
W Stremmel, HD Riedel, C Niederau… - European journal of …, 1993 - Wiley Online Library
… Increased iron absorption leads to a positive iron balance and accumulation of excess body
iron in genetic haemochromatosis. It is interesting that only specific organs are affected by …
iron in genetic haemochromatosis. It is interesting that only specific organs are affected by …
The molecular genetics of haemochromatosis
… in our understanding of key regulatory mechanisms of iron homeostasis. … called
haemochromatosis type 1, which is characterized by increased duodenal iron absorption and rapid …
haemochromatosis type 1, which is characterized by increased duodenal iron absorption and rapid …
The genetic basis of haemochromatosis
WJH Griffiths - Alimentary pharmacology & therapeutics, 2007 - Wiley Online Library
… genes associated with iron homeostasis will enhance our diagnostic certainty of primary
haemochromatosis … negative feedback of iron absorption in the gut is defective, iron continues to …
haemochromatosis … negative feedback of iron absorption in the gut is defective, iron continues to …
Haemochromatosis
PC Adams, JC Barton - The Lancet, 2007 - thelancet.com
… the haemochromatosis gene identified in population screening studies, who have been followed
up for many years, do not develop iron … A diagnosis of haemochromatosis based on iron …
up for many years, do not develop iron … A diagnosis of haemochromatosis based on iron …
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