The role of FhuD2 in iron (III)-hydroxamate transport in Staphylococcus aureus: demonstration that FhuD2 binds iron (III)-hydroxamates but with minimal …

MT Sebulsky, BH Shilton, CD Speziali… - Journal of Biological …, 2003 - ASBMB
… To overcome this iron shortage, bacteria have developed a variety of mechanisms to … little
available iron may exist within their environment. In particular, one important iron acquisition

Cystic Fibrosis Isolates of Pseudomonas aeruginosa Retain Iron-Regulated Antimicrobial Activity against Staphylococcus aureus through the Action of Multiple …

AT Nguyen, JW Jones, M Cámara, P Williams… - Frontiers in …, 2016 - frontiersin.org
… Early infection of the CF lung with Staphylococcus aureus is common, while Pseudomonas
… We recently showed that antimicrobial activity against S. aureus is enhanced by iron

Iron restriction induces the small-colony variant phenotype in Staphylococcus aureus

S Islam, AC Callender, QN Ho… - Frontiers in Microbiology, 2022 - frontiersin.org
… Transient SCV phenotypes are induced in genetically WT Staphylococcus aureus during
iron restriction. (A) WT colonies on TSA are larger and more pigmented than SCV colonies yet …

Evidence for siderophore‐dependent iron acquisition in group B Streptococcus

A Clancy, JW Loar, CD Speziali, M Oberg… - Molecular …, 2006 - Wiley Online Library
… to that described for FhuD2 from Staphylococcus aureus. The role of Fhu in siderophore-…
As the molecular mechanism for iron acquisition in GBS has not been elucidated, we sought to …

Expression of Multidrug Resistance Efflux Pump Gene norA Is Iron Responsive in Staphylococcus aureus

X Deng, F Sun, Q Ji, H Liang, D Missiakas… - Journal of …, 2012 - Am Soc Microbiol
Staphylococcus aureus utilizes efflux transporter NorA to pump out a wide range of structurally
aureus utilizes the iron-responsive transcriptional regulator Fur to activate iron acquisition

Efflux transporter of siderophore staphyloferrin A in Staphylococcus aureus contributes to bacterial fitness in abscesses and epithelial cells

H Nakaminami, C Chen, QC Truong-Bolduc… - Infection and …, 2017 - Am Soc Microbiol
… ) and staphyloferrin B (SB) of Staphylococcus aureus are essential for iron acquisition in the
iron-restricted environment of the host, … To assess the further function of SfaA and SbnD in S. …

Structural Basis for Xenosiderophore Utilization by the Human Pathogen Staphylococcus aureus

NP Endicott, E Lee, TA Wencewicz - ACS Infectious Diseases, 2017 - ACS Publications
… such as desferrioxamine B (DFOB) for iron acquisition. DFOB is used as a chelation
therapy to treat human iron overload diseases and has been linked to an increased risk of S. …

Metabolic sensor governing bacterial virulence in Staphylococcus aureus

Y Ding, X Liu, F Chen, H Di, B Xu… - Proceedings of the …, 2014 - National Acad Sciences
… of CcpE facilitates the release of iron from the host iron-sequestering protein. In sum,
these results clearly suggest that CcpE regulates iron acquisition in S. aureus. This notion is …

Evaluation of some Staphylococcus aureus iron-regulated proteins as vaccine targets

C Ster, F Beaudoin, MS Diarra, M Jacques… - Veterinary immunology …, 2010 - Elsevier
Staphylococcus aureus is an important pathogen that is … in an iron-restricted medium
in vitro. For the present study, six of those genes were selected from five different iron-acquisition

Non-transferrin-bound iron is associated with enhanced Staphylococcus aureus growth in hemodialysis patients receiving intravenous iron sucrose

A Barton Pai, MP Pai, J Depczynski… - American journal of …, 2006 - karger.com
… -binding protein which directly binds iron from host transferrin [14]. More recently, a new
pathway for iron acquisition was discovered in S. aureus that involves hemolysin and proteins …