… metabolism is regulated, we now have a better understanding of the molecular basis for
this interaction between iron and infection. Work in my laboratory has tried to capitalize on this …

… innate immune system is to limit iron availability to invading microbes in a … iron metabolism
in the setting of infection and delineate strategies used by human pathogens to overcome iron…

… In conclusion, the ability of microbial invaders to obtain growth-essential iron from the
host is an important component of virulence. The iron withholding capability of the host is …

… functional role mediated by both iron dependent and iron independent mechanisms. In this
… in regulating iron homeostasis and its role in host protection against microbial infection at the …

… for iron in a murine abscess mono-infection, but becomes restricted for iron upon co-infection …
Despite the clear importance of iron to bacterial infection, we know virtually nothing about …

… iron-limiting environment when attempting to colonize or invade mammalian hosts, the role of
iron in microbial infections … and there is little or no free iron to support microbial growth. The …

… of abnormal iron metabolism on susceptibility to infection. It is important to emphasize that
in infections that occur in otherwise normal individuals there is a decrease in serum iron levels …

… Moreover, the lattergroup observed that inges¬ tion of 1 gm of ferrous sulfate by normal
persons resulted in a threefold increase in plasma iron within two to four hours whereas infected …

… Inasmuch as successful invad-ers obviously obtain the iron … produce their own power-ful
iron binding compounds. No evi-… describe microbial metabolites that can vigorously extract iron …

… observed increase in secondary infections in patients with hemolytic conditions (… iron per
se, high serum iron saturation has been associated with a high incidence of microbial infections …