Nutritional immunity beyond iron: a role for manganese and zinc
TE Kehl-Fie, EP Skaar - Current opinion in chemical biology, 2010 - Elsevier
… to the struggle for iron between host and … infection, and this topic has been reviewed
elsewhere [5, 6]. This review will focus on the struggle for non-iron transition metals during infection, …
elsewhere [5, 6]. This review will focus on the struggle for non-iron transition metals during infection, …
[HTML][HTML] Iron and its relation to immunity and infectious disease
SJ Oppenheimer - The Journal of nutrition, 2001 - Elsevier
… interaction of iron and infection indicates a need for quantitative review of clinical morbidity
outcomes. Iron deficiency is … Iron treatment has been associated with acute exacerbations of …
outcomes. Iron deficiency is … Iron treatment has been associated with acute exacerbations of …
Nutritional iron turned inside out: intestinal stress from a gut microbial perspective
GAM Kortman, M Raffatellu… - FEMS microbiology …, 2014 - academic.oup.com
… a higher risk of infection because of the increased availability of iron to pathogenic bacteria
(… Another reason for the increased risk of infection is the direct effect of iron on the immune …
(… Another reason for the increased risk of infection is the direct effect of iron on the immune …
Microbial iron transport
ML Guerinot - Annual review of microbiology, 1994 - go.gale.com
… relationship between iron and infection of animals. … microbial siderophores as iron sources
must start with a brief review of our understanding of how plants themselves respond to iron …
must start with a brief review of our understanding of how plants themselves respond to iron …
Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis
VE Diaz-Ochoa, S Jellbauer, S Klaus… - … in cellular and infection …, 2014 - frontiersin.org
… metabolism is mediated by the hormone hepcidin, which controls host-protective responses
by integrating signals from iron status and threat of infection. Initially identified as an …
by integrating signals from iron status and threat of infection. Initially identified as an …
Infections and iron: too much of a good thing?
JA STOCKMAN - American Journal of Diseases of Children, 1981 - jamanetwork.com
… quantities of iron found in iron-fortified … iron and increased bacterial virulence and surveys
the existing clinical data related to iron administration and increased susceptibility to infection. …
the existing clinical data related to iron administration and increased susceptibility to infection. …
[HTML][HTML] Harnessing microbial iron chelators to develop innovative therapeutic agents
M Ribeiro, CA Sousa, M Simões - Journal of Advanced Research, 2022 - Elsevier
… tract infections and pneumonia. This siderophore has a mode of action based on a “Trojan
horse” strategy, using the iron … Recent progress has also been achieved concerning new iron …
horse” strategy, using the iron … Recent progress has also been achieved concerning new iron …
Host-microbial battle for iron: new opportunities to combat infection?
E Wine - Gastroenterology, 2024 - Elsevier
… Iron is essential for cellular function, especially with rapid growth during bacterial infection.
However, as intracellular iron is toxic, pathogens aim to get and hold onto iron while avoiding …
However, as intracellular iron is toxic, pathogens aim to get and hold onto iron while avoiding …
Siderophores in iron metabolism: from mechanism to therapy potential
BR Wilson, AR Bogdan, M Miyazawa… - Trends in molecular …, 2016 - cell.com
… One of the major challenges for pathogenic bacteria is in acquiring sufficient iron during
infection and post-infection inside the host. Competition between the host and pathogen for this …
infection and post-infection inside the host. Competition between the host and pathogen for this …
Microbial metabolite signaling is required for systemic iron homeostasis
… an iron-dependent mechanism that inhibits host iron transport and storage. Using a high-throughput
screen of microbial … factor of intestinal iron absorption and increase the iron-storage …
screen of microbial … factor of intestinal iron absorption and increase the iron-storage …