… Multiple sclerosis (MS) is primarily an autoimmune disorder of unknown origin. This review
focuses iron … Iron overload has been demonstrated in MS lesions, as a feature common with …

… Iron deposition in the human brain tissue occurs in the process of normal aging and … iron
levels in certain brain regions are also an increasingly recognized finding in multiple sclerosis (…

… , including multiple sclerosis (MS). In MS, it is still not clear whether iron deposition is an
epiphenomenon or a mediator of disease processes. In this review, the role of iron in the …

… in two of 13 multiple sclerosis subjects, apart from iron deposition in the substantia nigra
in … deposits, similar to those reported in this paper, in all of the five multiple sclerosis cases …

… in the CNS of patients with multiple sclerosis (MS). The mechanisms of abnormal iron
deposition in MS are not fully understood, nor do we know whether these deposits have adverse …

… In summary, increased iron deposition has been consistently reported to occur in MS, but
its role in pathogenetic processes of this disease has not yet been completely clarified. …

… in multiple sclerosis (MS). A recent hypothesis stated that CNS inflammation is induced by
perivenular iron deposits … iron deposits. This model was used to investigate the relationship of …

… in iron levels in the brains of patients with multiple sclerosis (MS), including increases in the
iron … Excessive free iron can be toxic, and accumulation of iron in MS has generally been …

… Iron may contribute to the pathogenesis and progression of multiple sclerosis (MS) due to
its … Our study focused on nonheme iron distribution and the expression of the iron-related …

… the localization of iron deposition in MS and AD brains indicates potential sites where iron
could … In the present study, the localization of iron deposits in MS brain tissue was reexamined …