… Here, we review evidence linking iron dysregulation to AD and the potential … disease
including amyloid beta (Aβ) and tau. Here we focus on the role of mitochondrial iron dysregulation, …

… homeostasis in the brain and explore how alterations in brain iron metabolism affect neuronal
function with emphasis on iron dysregulation in Alzheimer 0 s and Parkinson 0 s diseases. …

… of iron metabolism (ceruloplasmin and transferrin). Our aims were to identify new indicators
of disease … with that of iron in CSF and positively with the level of iron in plasma (Table 3). …

… The dysregulation of iron metabolism in Alzheimer's disease is not accounted for in the …
that impaired iron homeostasis is an early event in Alzheimer's disease progression. Iron …

… disease in this study. Taken together, we hypothesize that the alterations on … iron status
observed in patients could reflect an iron homeostasis dysregulation, particularly in cellular iron …

… between iron dysregulation and AD pathogenesis, discussed the potential of new hypothesis
related to iron … capable of targeting iron, with the expectation to draw more attention of iron …

… Hepcidin is a peptide hormone that controls dietary iron absorption and systemic iron … iron
efflux from the cell. At cell level, iron uptake, storage, and utilization are regulated by the iron …

… Background: Iron trafficking and accumulation is associated with Alzheimer’s disease (AD)
pathogenesis. However, the role of iron dyshomeostasis in early disease stages is uncertain. …

… These similarities suggest that the same changes leading to dysregulation of iron in brain
areas undergoing neuroinflammation as a result of kainate lesions, may also occur in the AD …

… While this behavior is responsible for the immense biological utility of iron, when dysregulated,
it … trafficking in the brain, which may be crucial for understanding how iron dysregulation …