[HTML][HTML] Drug repurposing: Iron in the fire for older drugs
HV Sonaye, RY Sheikh, CA Doifode - Biomedicine & Pharmacotherapy, 2021 - Elsevier
… to as drug repurposing, drug redirecting, drug retasking, drug … (USA), defined drug repurposing
as "studying the drugs that are … indications for the existing drugs, drugs currently in clinical …
as "studying the drugs that are … indications for the existing drugs, drugs currently in clinical …
Drug Repurposing: A strategic approach to addressing unmet medical needs
G Goel - … Journal of Pharma Professional's Research (IJPPR), 2024 - ijppronline.com
… : Drug repurposing, also known as drug repositioning or drug … This review article explores
the concept of drug repurposing, its … indications for existing drugs. Challenges in traditional …
the concept of drug repurposing, its … indications for existing drugs. Challenges in traditional …
Inclusion of nitrofurantoin into the realm of cancer chemotherapy via biology-oriented synthesis and drug repurposing
… Moreover, our laboratory has succeeded in repurposing the obsolete anti-amoebic … to
merge the drug repurposing approach with the concept of “biology-oriented drug synthesis” (BIODS…
merge the drug repurposing approach with the concept of “biology-oriented drug synthesis” (BIODS…
The updated landscape of tumor microenvironment and drug repurposing
… Drug repurposing in cancer The appeal of drug repurposing in cancer is increasing for … ,
etc.) of developing a new drug; (2) it reduces the failure risk of clinical trials because those these …
etc.) of developing a new drug; (2) it reduces the failure risk of clinical trials because those these …
Drug repurposing in cancer therapy: influence of patient's genetic background in breast cancer treatment
… drug repurposing … drug repurposing as a new window of opportunity for cancer therapy,
and specifically its application for precision medicine. We next selected some repurposed drugs …
and specifically its application for precision medicine. We next selected some repurposed drugs …
Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication
T Waters, KL Goss, SL Koppenhafer, WW Terry… - BMC cancer, 2020 - Springer
… drug repurposing screen, which includes 12 Ewing sarcoma cell lines, to identify drugs that
… of eltrombopag is due, in part, to the iron chelation properties of the drug [12,13,14]. Moreover…
… of eltrombopag is due, in part, to the iron chelation properties of the drug [12,13,14]. Moreover…
Exploring the Use of Intracellular Chelation and Non-Iron Metals to Program Ferroptosis for Anticancer Application
O Claudio-Ares, J Luciano-Rodríguez… - Inorganics, 2024 - mdpi.com
… of cancers to these drugs and the lack of specificity of the drugs for targeting cancer cells …
avenues for drug design. Evidence shows that ferroptosis, a relatively recently discovered iron-…
avenues for drug design. Evidence shows that ferroptosis, a relatively recently discovered iron-…
Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19
… ), N-protein image in the same area with “fire” false color LUT showing distinct morphologies
of … To rule out iron chelation as a potential mode of action, iron-saturated hololactoferrin and …
of … To rule out iron chelation as a potential mode of action, iron-saturated hololactoferrin and …
[图书][B] Computational Methods in Drug Discovery and Repurposing for Cancer Therapy
GP Nagaraju, V Amouda, AD Rao - 2023 - books.google.com
… The second set of review articles discusses important drug repurposing strategies that … drug
repurposing methods. The principles of computational drug designing and drug repurposing …
repurposing methods. The principles of computational drug designing and drug repurposing …
[图书][B] Application of Oxygenase Enzymes for Chemoenzymatic Synthesis of Natural Products & Exploration of Iron (II) α-Ketoglutarate Sequence Space for Non …
E King-Smith - 2022 - search.proquest.com
… the heirloom dining room table on fire distilling alcohol, youГve wo@… We show how an iron(ii)
ɑY@etoglutarate (Fe(ii)/ɑKG) lYlysine … We then repurpose enzymes from the platensimycin …
ɑY@etoglutarate (Fe(ii)/ɑKG) lYlysine … We then repurpose enzymes from the platensimycin …
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