Occurrence of CCSVI in patients with MS and its relationship with iron metabolism and varicose veins

PJ Van den Berg, GB Van den Berg… - European journal of …, 2013 - Wiley Online Library
… after being trained at their unit, and to examine its relationship with the peripheral venous
system and iron metabolism, which, to our knowledge, has never been documented before. …

Truth is in the eye of the beholder. A critical review of the CCSVI hypothesis

C Mayer, U Ziemann - Current Medical Literature, 2011 - search.proquest.com
iron metabolism is distorted by inflammation are hypothetical at present. The presence of
iron… MS but also other CNS diseases [81], and is not evidence in favor of the CCSVI hypothesis. …

[HTML][HTML] Oxidative stress related to iron metabolism in relapsing remitting multiple sclerosis patients with low disability

M Siotto, MM Filippi, I Simonelli, D Landi… - Frontiers in …, 2019 - frontiersin.org
… to iron metabolism in peripheral blood of stable Relapsing-Remitting MS with low disability.
We studied 60 Relapsing-Remitting MS patients (… However, the CCSVI hypothesis has been …

Anomalous venous blood flow and iron deposition in multiple sclerosis

AV Singh, P Zamboni - … of Cerebral Blood Flow & Metabolism, 2009 - journals.sagepub.com
… for iron homeostasis in vivo; it maintains the iron pool in the systemic circulation by binding
with iron … parallel in the mechanisms of iron deposition between CCSVI and CVD, we cannot …

The controversy of CCSVI and iron in multiple sclerosis: is ferritin the key?

SJ van Rensburg, R van Toorn - Neurology, 2010 - AAN Enterprises
… transport and regulate iron absorption from the gut are responsible for iron influx into the …
iron concentrations. In our own experience a third of patients with MS have decreased iron

P366 Iron homeostasis and multiple sclerosis

MM Meshref, I Al-Odat, S Alfayoumi… - Multiple Sclerosis …, 2022 - researchgate.net
… plasty for chronic cerebrospinal venous insufficiency (CCSVI): which needs further trials to
… to detecting changes iron homeostasis in the brain might help in providing the patients with …

[HTML][HTML] Iron and neurodegeneration in multiple sclerosis

M Khalil, C Teunissen… - Multiple sclerosis …, 2011 - ncbi.nlm.nih.gov
… Evidence for abnormal iron homeostasis in MS comes also from analyses of iron and iron-…
may argue against an etiologic role for CCSVI-related parenchymal iron deposition in MS [46]. …

Normal CSF ferritin levels in MS suggest against etiologic role of chronic venous insufficiency

V Worthington, J Killestein, MJ Eikelenboom… - Neurology, 2010 - AAN Enterprises
patient with MS as his or her own control. We hypothesized that ongoing parenchymal iron
deposition due to CCSVI … longitudinally investigating the iron metabolism in patients with MS. …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: diagnostic, pathogenetic, clinical and treatment perspectives

R Zivadinov, M Ramanathan, K Dolic… - Expert review of …, 2011 - Taylor & Francis
… for CCSVI in multiple sclerosis patients is still unknown. … of CCSVI in progressive MS patients
may suggest that CCSVI may play a … The cause–effect relationship between CCSVI and MS …

Brain hyperechogenicities are not associated with venous insufficiency in multiple sclerosis: a Pilot Neurosonology Study

C Krogias, R Gold, A Chan… - Journal of …, 2016 - Wiley Online Library
CCSVI and iron deposition in the brain of MS patients by correlating venous hemodynamic
parameters and iron … and regulate iron absorption from the gut are responsible for iron influx …