… in elderly and iron-deficient mice. Moreover, FPN deletion in the proximal tubules alleviated
ischemic acute kidney injury, possibly by upregulating FTH1 to limit catalytic iron and by …

… or iron recycling macrophages are iron-rich and act as iron stores … to iron and siderophore)
is taken up in renal proximal tubules … in renal ischemia-reperfusion injury (IRI), and the renal …

… recycled iron back to the bloodstream. The bulk of body iron requirements is satisfied by iron
recycling … NGAL administration before ischemic insult may attenuate kidney injury [79]. The …

… of iron in both acute kidney injury (AKI) and chronic kidney … by cellular iron content,
inflammation, ischaemia and oxidative … of iron-induced kidney injury by customized iron removal or …

… intestine, liver, and kidney. Iron plays a major role in acute kidney injury and has been a target
… did not eliminate, the increased iron levels in the kidney after ischemia-reperfusion injury. …

… Most of the iron in the body is derived from recycling of senescent red blood cells through …
tubular cells undergoes sequential death following ischemic kidney injury. In their study, …

… found to alleviate ischemic iAKI, perhaps by supplying iron for basic … an acute role of “catalytic
iron” at the onset of iAKI has been explored, it still remains unknown whether different iron …

… , iron metabolism has become a focus for novel therapeutic interventions for acute kidney
injury and chronic kidney disease, … extent inhibition of renal tubular iron recycling by hepcidin-…

… model of severe renal failure, ischemia-reperfusion injury, … of the disease, dramatically
protects the kidney and mitigates … with acute kidney damage, implicating the kidney as the major …

… that is required for iron incorporation and limiting toxicity. The … of FtH in acute kidney injury
(AKI) and renal iron handling by … of iron absorption and recycling, namely, release of iron from …