Irreversible electroporation (IRE): a narrative review of the development of IRE from the laboratory to a prostate cancer treatment

A Blazevski, MJ Scheltema, A Amin… - BJU …, 2020 - Wiley Online Library
Irreversible electroporation (IRE) is a novel technology that … This narrative review documents
the history of electroporation … clinical outcomes from the use of IRE in prostate cancer. …

Optimal parameters for the destruction of prostate cancer using irreversible electroporation

J Rubinsky, G Onik, P Mikus, B Rubinsky - The Journal of urology, 2008 - Elsevier
… the irreversible electroporation parameters that would reliably destroy prostate cancer cells.
… study has produced values for prostate cancer treatment with irreversible electroporation. …

Initial assessment of safety and clinical feasibility of irreversible electroporation in the focal treatment of prostate cancer

M Valerio, PD Stricker, HU Ahmed… - … cancer and prostatic …, 2014 - nature.com
… This figure shows a representation of the electrodes used for irreversible electroporation with
… lesion with limited damage to surrounding structures after focal irreversible electroporation. …

[HTML][HTML] Prostate cancer treatment with Irreversible Electroporation (IRE): Safety, efficacy and clinical experience in 471 treatments

E Guenther, N Klein, S Zapf, S Weil, C Schlosser… - PloS one, 2019 - journals.plos.org
Background Irreversible Electroporation (IRE) is a novel image-guided tissue ablation
technology that induces cell death via very short but strong pulsed electric fields. IRE has been …

[HTML][HTML] Irreversible electroporation for prostate cancer

S Ong, M Leonardo, T Chengodu, D Bagguley… - Life, 2021 - mdpi.com
… This narrative review describes the IRE procedure, summarises the available data about
irreversible electroporation as a focal therapy for prostate cancer, and discusses future …

Focal irreversible electroporation as primary treatment for localized prostate cancer

W van den Bos, MJ Scheltema… - BJU …, 2018 - Wiley Online Library
… Quality of life after primary and salvage irreversible electroporation (IRE), measured using
the Expanded Prostate Cancer Index Composite (EPIC) questionnaire including urinary, …

First human trial of high-frequency irreversible electroporation therapy for prostate cancer

S Dong, H Wang, Y Zhao, Y Sun… - Technology in cancer …, 2018 - journals.sagepub.com
… are spared during the treatment, which leads to the retention of prostate function. However,
… in human prostate cancer ablation. There are 40 male patients with prostate cancer aged …

Nanoknife electroporation ablation trial: a prospective development study investigating focal irreversible electroporation for localized prostate cancer

M Valerio, L Dickinson, A Ali, N Ramachadran… - The Journal of …, 2017 - auajournals.org
Irreversible electroporation has attractive attributes for focal ablation, namely nonthermal …
We report a prospective development study investigating focal irreversible electroporation. …

Irreversible electroporation: first patient experience focal therapy of prostate cancer

G Onik, B Rubinsky - Irreversible electroporation, 2010 - Springer
… new prostate cancer management … prostate cancer using cryo-ablation in 2002 (2). Other
clinical series using cryo-ablation to focally treat prostate cancer have shown excellent cancer

Histopathological outcomes after irreversible electroporation for prostate cancer: results of an ablate and resect study

W Van Den Bos, RR Jurhill, DM De Bruin… - The Journal of …, 2016 - auajournals.org
… Sixteen patients with prostate cancer underwent an irreversible electroporation ablation …
For histopathological examination of the prostate, whole mounted tissue slices were examined …