Long-chain polyunsaturated fatty acids protect the heart against ischemia/reperfusion-induced injury via a MAPK dependent pathway
AM Engelbrecht, P Engelbrecht, S Genade… - Journal of molecular and …, 2005 - Elsevier
… simulated ischaemia (SI) and reperfusion (R). Myocytes isolated from 1-2 day old Wistar rat
… p38 phosphorylation during reperfusion. The mechanism of action of ARA on the MAPKs was …
… p38 phosphorylation during reperfusion. The mechanism of action of ARA on the MAPKs was …
ERK and p38 MAPK, but not NF-κB, are critically involved in reactive oxygen species–mediated induction of IL-6 by angiotensin II in cardiac fibroblasts
M Sano, K Fukuda, T Sato, H Kawaguchi… - Circulation …, 2001 - Am Heart Assoc
… MAPK phosphorylation. We first confirmed that Ang II elicits a rapid and robust phosphorylation
of p38 MAPK… inhibited Ang II–induced phosphorylation of p38 MAPK, ERK1/2 and JNK-1 (…
of p38 MAPK… inhibited Ang II–induced phosphorylation of p38 MAPK, ERK1/2 and JNK-1 (…
17-β-Estradiol decreases p38 MAPK-mediated myocardial inflammation and dysfunction following acute ischemia
M Wang, BM Tsai, KM Reiger, JW Brown… - Journal of molecular and …, 2006 - Elsevier
… performed to measure p38 MAP kinase and apoptosis-related proteins. Heart tissue was …
the following primary antibodies: p38 MAP kinase antibody, phosphor-p38 MAP kinase (Thr180/…
the following primary antibodies: p38 MAP kinase antibody, phosphor-p38 MAP kinase (Thr180/…
Immunohistochemical localization of mitogen-activated protein kinase (MAPK) family and morphological changes in rat heart after ischemia-reperfusion injury
Z Naito, M Kudo, G Xu, R Nishigaki… - Medical Electron …, 2000 - Springer
… ) family is considered to be activated by stress, but the role of the MAPK … of MAPKs such as
the extracellular responsive kinase (ERK), c-jun Nterminal kinase (JNK), and p38 MAPK (p38)…
the extracellular responsive kinase (ERK), c-jun Nterminal kinase (JNK), and p38 MAPK (p38)…
p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation
F Gao, TL Yue, DW Shi, TA Christopher… - Cardiovascular …, 2002 - academic.oup.com
… The data show that a transient (<30 min), moderate (two- to threefold) increase in p38
MAPK activity was observed in the hearts subjected to ischemia without reperfusion (data not …
MAPK activity was observed in the hearts subjected to ischemia without reperfusion (data not …
[PDF][PDF] Effect of ulinastatin on myocardial ischemia-reperfusion injury through JNK and P38 MAPK signaling pathways.
ZH Yang, YJ Lu, KP Gu, ZY Xiang… - European Review for …, 2019 - europeanreview.org
… p38 MAPK and JNK in serum were detected via Western blotting. Furthermore, the correlations
of serum p38 MAPK … Meanwhile, the mRNA expressions of p38 MAPK and JNK in the UTI …
of serum p38 MAPK … Meanwhile, the mRNA expressions of p38 MAPK and JNK in the UTI …
BYD ameliorates oxidative stress-induced myocardial apoptosis in heart failure post-acute myocardial infarction via the P38 MAPK-CRYAB signaling pathway
Y Zhang, C Li, H Meng, D Guo, Q Zhang, W Lu… - Frontiers in …, 2018 - frontiersin.org
… P38 mitogen-activated protein kinase (MAPK)-αB-crystallin (CRYAB) signaling pathway was
activated by BYD treatment, and the P38 MAPK … P38 MAPK cascade pathway (Figure 6A). …
activated by BYD treatment, and the P38 MAPK … P38 MAPK cascade pathway (Figure 6A). …
Mitochondrial kinase signalling pathways in myocardial protection from ischaemia/reperfusion-induced necrosis
… of female hearts to ischaemia/reperfusion injury than that of male hearts. Lagranha et al. …
Kinase activity of PKC-ε was unnecessary for this physical interaction of PKC-ε with MAPKs, but …
Kinase activity of PKC-ε was unnecessary for this physical interaction of PKC-ε with MAPKs, but …
Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases
M Capano, M Crompton - Biochemical Journal, 2006 - portlandpress.com
… ischaemia activated both Bax translocation and p38 MAPK, … ischaemia and reperfusion
activate both the p38 MAPK and … heart, only the p38 MAPK pathway is activated by ischaemia …
activate both the p38 MAPK and … heart, only the p38 MAPK pathway is activated by ischaemia …
Ischemic preconditioning or p38 MAP kinase inhibition attenuates myocardial TNF α production and mitochondria damage in brief myocardial ischemia
H Kimura, K Shintani-Ishida, M Nakajima, S Liu… - Life sciences, 2006 - Elsevier
… of p38 MAP kinase and S6 kinase after ischemia were inhibited by IP or p38 MAP kinase …
heart” by immunoblotting using phospho-specific antibodies (Fig. 5). The phosphorylation of …
heart” by immunoblotting using phospho-specific antibodies (Fig. 5). The phosphorylation of …