… The two lines of studies performed thus far have sought to determine (1) whether
preconditioning induces the activation of p38 MAPKs and (2) whether inhibition of p38 MAPKs …

… regulated protein kinase (ERK), p38 MAPK (p38), and c-Jun … cardiac MAPKs, we examined
the activities of 3 major MAPK … that the 3 major MAPK subfamily members, ERK, p38, and JNK…

… of p38 MAPK cascade may be one underlying mechanism of Scu's beneficial effects on MI
hearts… of the active form of p38 MAPK, phospho-p38 MAPK, while having no effect on the total …

… 14 and p38-MAPKδ 15 … The levels of p38-MAPKγ and p38-MAPKδ transcripts in human
heart cDNA libraries are low compared with those of p38-MAPK(α) and p38-MAPKβ, 16 but it is …

… is reduced in MK2 −/− compared to MK2 +/+ hearts, we interrogated activation of p38 MAPK
… of total and phosphorylated p38 MAPK in MK2 +/+ and MK2 −/− hearts after control perfusion …

… in p38 MAP kinase phosphorylation during ischemia per se has been described in several
[1–3] but not all studies (for review see [4,5]). The p38 MAP kinase … preconditioned hearts only …

… p38 (P-p38) MAPK is the active form of p38 MAPK. However, it is currently unclear whether
P-p38 MAPK … both in rats with myocardial ischaemia and in mice with streptozotocin-induced …

… and the transition to heart failure. Myocardial p38 MAPK is rapidly activated in rats after MI
induced by coronary artery ligation (10). Sustained p38 MAPK activation in the heart has been …

… alpha during myocardial ischaemia results in myocardial … of p38alpha particularly during
myocardial ischaemia. We have … We have characterised an analogue sensitive form of p38 …

… We hypothesized that p38 MAPK activation is involved in the … inhibition of p38 MAPK activation
could improve contractility. … isolated mouse heart model, we have shown that p38 MAPK …