High intraocular pressure-induced ischemia and reperfusion injury in the optic nerve and retina in rats

M Adachi, K Takahashi, M Nishikawa, H Miki… - Graefe's archive for …, 1996 - Springer
ischemia-reperfusion injury and the extent to which optic nerve damage correlates with
the duration if ischemia due to high intraocular pressure (… than with 45 min ischemiareperfusion

A mouse model of retinal ischemia-reperfusion injury through elevation of intraocular pressure

MJ Hartsock, H Cho, L Wu, WJ Chen, J Gong… - JoVE (Journal of …, 2016 - jove.com
… procedure for inducing retinal ischemia-reperfusion injury by elevated intraocular pressure
in mice. Retinal ischemia-reperfusion injury by elevated intraocular pressure serves to model …

[HTML][HTML] Activation of autophagy in a rat model of retinal ischemia following high intraocular pressure

A Piras, D Gianetto, D Conte, A Bosone, A Vercelli - PloS one, 2011 - journals.plos.org
intraocular pressure, which causes retinal ischemia and neuronal death. Rat ischemia/reperfusion
autophagy in GCL-neurons following ischemia/reperfusion, using acid phosphatase (…

Retinal damage caused by high intraocular pressure–induced transient ischemia is prevented by coenzyme Q10 in rat

C Nucci, R Tartaglione, A Cerulli, R Mancino… - International Review of …, 2007 - Elsevier
… Using an established animal model of retinal ischemia/reperfusion here, we show that … of
reperfusion and delayed apoptosis in the RGC layer is seen at 24 h. Intraocular administration …

[HTML][HTML] Involvement of the endocannabinoid system in retinal damage after high intraocular pressure–induced ischemia in rats

C Nucci, V Gasperi, R Tartaglione… - … & Visual Science, 2007 - tvst.arvojournals.org
… 45 minutes of ischemia followed by 12 hours of reperfusion. … In rat retina, ischemic insult
followed by reperfusion resulted in … Retinal ischemia-reperfusion decreased the expression of …

Evaluation of potential topical and systemic neuroprotective agents for ocular hypertension‐induced retinal ischemiareperfusion injury

YI Chen, YJ Lee, DA Wilkie, CT Lin - Veterinary ophthalmology, 2014 - Wiley Online Library
… the detrimental effect of high intraocular pressure-induced ischemia-reperfusion injury. In …
the protective effects of various neuroprotective agents against ischemia/reperfusion injury. …

[HTML][HTML] Protective limb remote ischemic post-conditioning against high-intraocular-pressure-induced retinal injury in mice

QJ Zhu, L Zhang, SY Lyu, ZJ Cui… - International Journal of …, 2022 - ncbi.nlm.nih.gov
… artery occlusion induced retinal ischemic injury, and was … on high intraocular pressure (IOP)-induced
retinal ischemia injury … In our study, LRIC in ischemic reperfusion animals reduced …

Neurochemical evidence to implicate elevated glutamate in the mechanisms of high intraocular pressure (IOP)-induced retinal ganglion cell death in rat

C Nucci, R Tartaglione, L Rombolà, LA Morrone… - Neurotoxicology, 2005 - Elsevier
… High intraocular pressure (IOP)-induced ischemia is a model for retinal neurodegeneration
… that IOP-induced retinal ischemia for 45 min, followed by 24-h reperfusion, causes severe …

Histological assessment of rat retinas with ischemia-reperfusion injury

J San Cristóbal Epalza, T Palomares… - European Surgical …, 2021 - karger.com
… For inducing IRI, we increased the intraocular pressure (IOP) above the baseline SBP by
placing a catheter inside the femoral artery. Increasing IOP above SBP leads to collapse of the …

[HTML][HTML] Ocular perfusion pressure and ocular blood flow in glaucoma

AP Cherecheanu, G Garhofer, D Schmidl… - Current opinion in …, 2013 - Elsevier
… Increased intraocular pressure and ischemia at the post-… factor that may be enhanced by
ischemia associated with low OPP. … Ischemia and ischemia/reperfusion are classic triggers for …