Background— High-mobility group box-1 (HMGB1) is a nuclear factor released by necrotic
cells and by activated immune cells. HMGB1 signals via members of the toll-like receptor …

… High mobility group box 1 (HMGB1) is a NF released extracellularly as a late mediator of …
ischemic injury activates inflammatory signaling through the release of high-mobility group …

… -mobility group box 1 (HMGB1) is an abundant chromatin-associated nuclear protein and
released into the extracellular milieu during liver ischemia-reperfusion (I/R)… High mobility group …

… high mobility group box 1 (HMGB1) is an important inflammatory mediator involved in the
pathogenesis of liver ischemia/reperfusion (I/… of retaining high mobility group proteins inside the …

… ‑mobility group box‑1 (HMGB1) acts as a proinflammatory cytokine that triggers and amplifies
the inflammation cascade following ischemia/reperfusion … ischemia and 48 h reperfusion. In …

… We demonstrate that the elaboration of the nuclear protein High Mobility Group-Box 1 (HMG-B1)
caused by hindlimb occlusion may be an important contributor to the distant protective …

… after ischemia reperfusion … group decreased continuously after ischemia-reperfusion injury,
the creatinine levels were significantly higher than those seen in the sham operation group (…

… Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver
ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection. …

… Kidney ischemia–reperfusion injury (IRI) is an inevitable … pathogenesis of IRI include
high-mobility group box 1 (HMGB1)… , such as a short period of ischemia given before a much …

BACKGROUND: High-mobility group box 1 (HMGB1) is a mediator of inflammation with
dose-dependent effects. In the setting of regional myocardial infarction, a high-dose HMGB1 …