new therapetic approaches in the management of ischemia reperfusion injury and cardiometabolic diseases: opportunities and challenges

J Ren, Y Zhang - Current Drug Targets, 2017 - ingentaconnect.com
ischemia reperfusion (I/R) injury being the most important risk factors [1-3]. Both ischemiareperfusion
molecular mechanisms underlying ischemic reperfusion injury and cardiometabolic …

Ferroptosis: opportunities and challenges in myocardial ischemiareperfusion injury

W Zhao, Y Zhou, T Xu, Q Wu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
… the process of myocardial ischemia-reperfusion injury (MIRI) … artery of mice in the
ischemia-reperfusion injury(IRI) model after … alleviate organ injury induced by ischemic reperfusion

Opportunities and challenges of pain-related myocardial ischemia-reperfusion injury

W Jiang, Y Yin, X Gu, Z Zhang, H Ma - Frontiers in Physiology, 2022 - frontiersin.org
… Direct IPC comprises a few short ischemic-reperfusion sessions before the heart is
subjected to sustained ischemia-reperfusion. RIPC is the temporary ischemic treatment of other …

Ischemia reperfusion injury: Opportunities for nanoparticles

X Zang, J Zhou, X Zhang, Y Han… - ACS biomaterials science …, 2020 - ACS Publications
Ischemia reperfusion injury is a pathophysiological condition associated with cerebral stroke,
… a challenge due to the unpredictable nature of ischemia. Unlike preconditioning before …

Refocusing neuroprotection in cerebral reperfusion era: new challenges and strategies

XY Xiong, L Liu, QW Yang - Frontiers in neurology, 2018 - frontiersin.org
… This approach has created great opportunities for better estimating the effectiveness of …
Because the cerebral ischemia reperfusion has been shown in multivariate analyses is a …

Ischemia/reperfusion injury revisited: an overview of the latest pharmacological strategies

ROS Soares, DM Losada, MC Jordani, P Évora… - International journal of …, 2019 - mdpi.com
Ischemia/reperfusion injury (IRI) permeates a variety of … ischemia and reperfusion are
abundant in the literature and they consist of several strategies, such as applying pre-ischemic

Challenges in early clinical drug development for ischemia-reperfusion injury in kidney transplantation

S O'Neill, K Gallagher, J Hughes… - Expert opinion on …, 2015 - Taylor & Francis
… Expert opinion: Translating pharmacological strategies for reducing IRI is highly challenging
at … opportunities to utilise pharmacological agents earlier in the process of transplantation. …

Oxidative stress evaluation in ischemia reperfusion models: characteristics, limits and perspectives

P Chazelas, C Steichen, F Favreau, P Trouillas… - International Journal of …, 2021 - mdpi.com
Ischemia reperfusion injury is a complex process consisting … in the study of ischemia reperfusion.
Applying chemistry as … in vitro hypoxia as a surrogate for ischemia. Having identified the …

[HTML][HTML] Myocardial reperfusion injury and oxidative stress: Therapeutic opportunities

J González-Montero, R Brito, AIJ Gajardo… - World journal of …, 2018 - ncbi.nlm.nih.gov
reperfusion, no-reflow, myocardial stunning, and reperfusion … accounting for the myocardial
ischemia reperfusion injury, it … reperfusion therapy in order to limit the oxidative challenge

[HTML][HTML] Current mechanistic concepts in ischemia and reperfusion injury

MY Wu, GT Yiang, WT Liao, APY Tsai… - Cellular Physiology and …, 2018 - karger.com
… induced by ischemia-reperfusion injury presents a challenge for physicians to …
ischemia-reperfusion injury may provide a strong foundation not only for novel therapeutic …