Update on mechanisms of ischemic acute kidney injury

P Devarajan - Journal of the American Society of Nephrology, 2006 - journals.lww.com
Acute renal failure (ARF), classically defined as an abrupt decrease in kidney function that
leads to accumulation of nitrogenous wastes such as blood urea nitrogen and creatinine, is a …

Pathophysiology of ischemic acute kidney injury

AA Sharfuddin, BA Molitoris - Nature Reviews Nephrology, 2011 - nature.com
Acute kidney injury (AKI) as a consequence of ischemia is a common clinical event leading
to unacceptably high morbidity and mortality, development of chronic kidney disease (CKD), …

[HTML][HTML] Mechanisms and therapeutic targets of ischemic acute kidney injury

SJ Han, HT Lee - Kidney research and clinical practice, 2019 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) supplanted the older term acute renal … In 2007, the Acute Kidney
Injury Network (AKIN) … the Risk, Injury, and Failure; and Loss, and End-stage kidney disease …

[HTML][HTML] Cellular pathophysiology of ischemic acute kidney injury

JV Bonventre, L Yang - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here,
we review the major components of this dynamic process, which involves hemodynamic …

[HTML][HTML] Advances in understanding ischemic acute kidney injury

R Munshi, C Hsu, J Himmelfarb - BMC medicine, 2011 - Springer
Acute kidney injury (AKI) is independently associated with increased morbidity and mortality.
Ischemiaischemic AKI. This paper discusses recent developments in the understanding of …

Mouse model of ischemic acute kidney injury: technical notes and tricks

Q Wei, Z Dong - American Journal of Physiology-Renal …, 2012 - journals.physiology.org
Renal ischemia-reperfusion leads to acute kidney injury (AKI), a major kidney disease … used
to study the pathogenic mechanisms of ischemic AKI and to test renoprotective strategies. …

[HTML][HTML] Ischemic and non-ischemic acute kidney injury cause hepatic damage

F Golab, M Kadkhodaee, M Zahmatkesh, M Hedayati… - Kidney international, 2009 - Elsevier
… that acute kidney ischemia or … acute kidney failure, the severity of kidney injury and its
complications. Epidemiological studies have identified a close relationship between kidney injury

[HTML][HTML] The endothelial cell in ischemic acute kidney injury: implications for acute and chronic function

DP Basile - Kidney international, 2007 - Elsevier
… Recent evidence suggests that injury to the … ischemic acute kidney injury (AKI). Established
and new data support the suggestion that vascular injury, in particular, endothelial cell injury, …

The innate immune response in ischemic acute kidney injury

HR Jang, H Rabb - Clinical immunology, 2009 - Elsevier
… in ischemic acute kidney injury, as well as present recent data on a modulatory role for
lymphocytes. In ischemic acute kidney injury, … roles in ischemic acute kidney injury in this section. …

Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury

M Horbelt, SY Lee, HE Mang… - American Journal …, 2007 - journals.physiology.org
… to the pathophysiology of ischemic acute kidney injury (AKI). In … ischemic AKI. Three-dimensional
reconstructions of microvascular networks obtained 24 h following acute ischemic injury