Ischemic postconditioning protects against focal cerebral ischemia by inhibiting brain inflammation while attenuating peripheral lymphopenia in mice

SP Joo, W Xie, X Xiong, B Xu, H Zhao - Neuroscience, 2013 - Elsevier
… infiltration of leukocytes, including macrophages, T cells and B cells in the ischemic brain.
We also found that IPostC attenuated lymphopenia in the peripheral blood and spleen. …

Cerebral ischemic postconditioning plays a neuroprotective role through regulation of central and peripheral glutamate

J You, L Feng, M Xin, D Ma… - BioMed Research …, 2018 - Wiley Online Library
… This helps to prevent the loss of peripheral immune cells, attenuates peripheral
lymphocyte DNA damage and then preventing the loss of lymphocytic function in blood [4]. …

[HTML][HTML] Peripheral mechanisms of remote ischemic conditioning

J Yang, F Shakil, S Cho - Conditioning medicine, 2019 - ncbi.nlm.nih.gov
… This review will focus on the peripheral factors that account for the induction of tolerance. …
, peripheral neural pathways, humoral factors in circulation, and the peripheral immune system. …

The changes of systemic immune responses during the neuroprotection induced by remote ischemic postconditioning against focal cerebral ischemia in mice

C Liu, J Yang, C Zhang, X Geng, H Zhao - Neurological Research, 2019 - Taylor & Francis
… limb may transfer a protective signal to the ischemic brain via the peripheral immune system…
The characteristic symptom of SIID is lymphopenia, which is characterized by decreased …

[HTML][HTML] Effects of remote ischemic postconditioning on the pro-inflammatory neutrophils of peripheral blood in acute cerebral infarction

Z Liang, L Qiu, X Wang, L Feng, Y Hao, F Yang… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
peripheral blood neutrophils in patients with ACI and determine whether remote ischemic
postconditioning … = 14; 7-day ischemia adaptation [complete ischemia of both upper extremities …

[HTML][HTML] The underlying mechanisms involved in the protective effects of ischemic postconditioning

R Xie, J Li, H Zhao - Conditioning medicine, 2018 - ncbi.nlm.nih.gov
… Cerebral ischemic postconditioning (PostC) refers to a series of brief ischemia and reperfusion
(I/R) cycles applied at the onset of reperfusion following an ischemic event. PostC has …

Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo

RK Kharbanda, M Peters, B Walton, M Kattenhorn… - Circulation, 2001 - Am Heart Assoc
… In the present study, there was evidence for activation of peripheral neutrophils (assessed
by surface CD11b expression) after reperfusion, consistent with a systemic response. …

Cerebrovascular ischemic protection by pre-and post-conditioning

JM Gidday - Brain Circulation, 2015 - journals.lww.com
… [ 41 , 45 , 46 , 47 ] Finally, in postconditioned animals, the extent of peripheral lymphopenia
following stroke is attenuated in postconditioned animals,[ 45 ] as is the extent of monocyte …

[HTML][HTML] The angiogenic effects of ischemic conditioning in experimental critical limb ischemia

R Karakoyun, C Koksoy, TU Yilmaz, H Altun… - European Journal of …, 2014 - Elsevier
ischemia–reperfusion syndromes. Several studies have shown the beneficial effects of
preconditioning and post-conditioning in different ischemia–… of the lymphocyte population (R 1). …

Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation

K Vaibhav, M Braun, MB Khan, S Fatima… - Journal of Experimental …, 2018 - rupress.org
… limb ischemic post-conditioning (RIC), the repetitive inflation–deflation of a blood pressure
cuff on a limb, noninvasively reduced ischemic … in peripheral blood after traumatic brain injury. …