Targeting the immune system for ischemic stroke
… Acute ischemic stroke results in the activation of a series of inflammatory events, mediated …
, as well as infiltrating immune cells from the periphery. Some immune cells such as T helper (…
, as well as infiltrating immune cells from the periphery. Some immune cells such as T helper (…
Rational modulation of the innate immune system for neuroprotection in ischemic stroke
D Amantea, G Micieli, C Tassorelli… - Frontiers in …, 2015 - frontiersin.org
… the immune system has been involved in ischemic tolerance… ischemic stroke should be
aimed at blocking the detrimental effects, while promoting the beneficial responses of the immune …
aimed at blocking the detrimental effects, while promoting the beneficial responses of the immune …
Brain-immune interactions and ischemic stroke: clinical implications
H Kamel, C Iadecola - Archives of neurology, 2012 - jamanetwork.com
… In addition, we highlight the many gaps in our understanding of the role of the immune system
in CNS injury and examine promising avenues of future investigation. Although relevant to …
in CNS injury and examine promising avenues of future investigation. Although relevant to …
Immunological consequences of ischemic stroke
A Vogelgesang, KJ Becker… - Acta Neurologica …, 2014 - Wiley Online Library
… Recent observations have revealed that stroke also alters the function of the immune
system and vice versa: At the site of the infarct, a local inflammatory response develops that …
system and vice versa: At the site of the infarct, a local inflammatory response develops that …
Aging immune system in acute ischemic stroke: a transcriptomic analysis
GP Sykes, J Kamtchum-Tatuene, S Falcione… - Stroke, 2021 - Am Heart Assoc
… The role of an aging immune system in patients with ischemic stroke … of stroke risk and
outcome. This study assessed the aging immune system in patients with acute ischemic stroke by …
outcome. This study assessed the aging immune system in patients with acute ischemic stroke by …
Stroke and the immune system: from pathophysiology to new therapeutic strategies
R Macrez, C Ali, O Toutirais, B Le Mauff… - The Lancet …, 2011 - thelancet.com
… immune-based stroke therapies. We postulate that a better understanding of the interactions
between the immune system … Pathophysiologic mechanisms of acute ischemic stroke: an …
between the immune system … Pathophysiologic mechanisms of acute ischemic stroke: an …
Immune pathways in etiology, acute phase, and chronic sequelae of ischemic stroke
… innate and adaptive immune systems influence cerebral damage cascades after ischemic
stroke. … influence both outcome after stroke and recurrence risk for further stroke. In addition, …
stroke. … influence both outcome after stroke and recurrence risk for further stroke. In addition, …
Inflammatory mechanisms in ischemic stroke: therapeutic approaches
SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
… viability in the vicinity of the ischemic core. This review will discuss the … ischemic stroke and
potential therapeutic strategies that target neuroinflammation and the innate immune system…
potential therapeutic strategies that target neuroinflammation and the innate immune system…
Immune cells in the BBB disruption after acute ischemic stroke: targets for immune therapy?
Y Qiu, C Zhang, A Chen, H Wang, Y Zhou… - Frontiers in …, 2021 - frontiersin.org
… blocks a variety of circulating leukocytes from entering the CNS and prevents CNS-specific
antigens from infiltrating into the peripheral immune system. The extravasation of peripheral …
antigens from infiltrating into the peripheral immune system. The extravasation of peripheral …
The involvement and therapy target of immune cells after ischemic stroke
Z Jian, R Liu, X Zhu, D Smerin, Y Zhong, L Gu… - Frontiers in …, 2019 - frontiersin.org
… ischemic brain injury. In this review, we will discuss the role of different immune cells after
stroke … , T cells act on neurons indirectly through the interaction with the innate immune system. …
stroke … , T cells act on neurons indirectly through the interaction with the innate immune system. …
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