Inflammation as a therapeutic target in acute ischemic stroke treatment

A Tuttolomondo, R Di Sciacca… - Current topics in …, 2009 - ingentaconnect.com
… During the course of brain ischemia, inflammatory mechanisms both intrinsic to brain as
well as blood are among the important mediators of focal cerebral injury [1]. With the onset of …

Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke

C Yang, KE Hawkins, S Doré… - American Journal of …, 2019 - journals.physiology.org
… the neuroinflammatory mechanisms of BBB disruption in ischemic stroke. Specifically, the …
), and inflammatory cells in the regulation of BBB disruption in ischemic stroke are emphasized…

Inflammation in ischemic stroke subtypes

A Tuttolomondo, D Di Raimondo… - Current …, 2012 - ingentaconnect.com
… These results suggest a potential role of adipose pro-inflammatory cytokines induced by the
… acute ischemic stroke. During the course of brain ischemia, inflammatory mechanisms both …

[HTML][HTML] Update on inflammatory biomarkers and treatments in ischemic stroke

A Bonaventura, L Liberale, A Vecchié… - International journal of …, 2016 - mdpi.com
… Activated PMNs enhance ischemic damage mainly through three mechanisms, such as
reactive oxygen species (ROS) and protease production [19], cytokine-mediated enhanced …

The interplay of MicroRNAs in the inflammatory mechanisms following ischemic stroke

SE Khoshnam, W Winlow… - Journal of Neuropatholgy …, 2017 - academic.oup.com
… In this review, we focus on the miRNAs associated with ischemic neuroinflammation and …
of deleterious inflammatory responses following ischemic stroke. Inflammation, miRNA, Stroke

Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets

JY Kim, M Kawabori, MA Yenari - Current medicinal chemistry, 2014 - ingentaconnect.com
Ischemic stroke is more commonly encountered compared to hemorrhagic stroke, and leads
to tissue death by ischemia … Inflammation is known to result as a result of ischemic injury, …

Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis

P Deb, S Sharma, KM Hassan - Pathophysiology, 2010 - Elsevier
Inflammation and stroke … some form of inflammatory mechanism plays a role in development
and progression of stroke, especially in the setting of cerebral ischemia due to subarcahnoid …

[PDF][PDF] Inflammation in the pathogenesis of ischemic stroke

J Pei, X You, Q Fu - Front Biosci (Landmark Ed), 2015 - article.imrpress.com
… However, the precise mechanism of inflammation in ischemic stroke remains elusive; …
of ischemic stroke. In this review, we discuss the role of pro-inflammatory and anti-inflammatory

Inflammatory mechanisms, arteriosclerosis and ischemic stroke: clinical data and perspectives

LC Alvaro-Gonzalez, MM Freijo-Guerrero… - Revista de …, 2002 - europepmc.org
ischemic atherotrombotic stroke is the most frequent form of the last one. In this sense we
review herein the mechanisms … DEVELOPMENT: It is understood as an inflammatory disease, …

The role of selected pro-inflammatory cytokines in pathogenesis of ischemic stroke

H Pawluk, A Woźniak, G Grześk… - … interventions in aging, 2020 - Taylor & Francis
… and inflammatory reaction constitute the key mechanisms involved … -inflammatory factors
of neuronal, glial and neuroendocrine origin, as well as inflammatory markers in ischemic stroke