Mechanisms of ischemic brain damage

KP Doyle, RP Simon, MP Stenzel-Poore - Neuropharmacology, 2008 - Elsevier
… A thrombosis, an embolism or systemic hypo-perfusion, all of which result in a restriction of
blood flow to the brain, can cause an ischemic stroke, which results in insufficient oxygen and …

Ischemic stroke, obesity, and the anti‐inflammatory role of melatonin

N Yawoot, P Govitrapong, C Tocharus, J Tocharus - Biofactors, 2021 - Wiley Online Library
… Based on this information, it seems that ischemic stroke induces severe brain inflammation
via several mechanisms. The response can be demonstrated by an increase of various …

Mechanisms of ischemic brain injury

V Janardhan, AI Qureshi - Current cardiology reports, 2004 - Springer
… for acute ischemic stroke [2]. However, the majority of patients with acute ischemic stroke do
not present to the hospital within 3 hours. Understanding the mechanisms of ischemic brain …

Pathophysiology of ischemic stroke: role of oxidative stress

S Orellana-Urzúa, I Rojas, L Líbano… - Current …, 2020 - ingentaconnect.com
Inflammation in ischemic stroke: mechanisms, consequences and possible drug targets.
CNS Neurol Disord Drug Targets 2014; 13(8): 1378-96. http://dx.doi.org/10.2174/…

Brain to periphery in acute ischemic stroke: mechanisms and clinical significance

P Cui, LD McCullough, J Hao - Frontiers in neuroendocrinology, 2021 - Elsevier
… of ischemic stroke have been increasing worldwide. In addition to focal brain damage, acute
ischemic stroke … contribute to the progression of ischemic brain injury, which accounts for the …

Pathophysiology and biomarkers in acute ischemic stroke–a review

Y Guo, P Li, Q Guo, K Shang, D Yan, S Du… - Tropical Journal of …, 2013 - ajol.info
… and increases the inflammatory injury [71]. Such different results suggest a complex role
of TNFα in inflammatory mechanisms. As an important indicator of inflammation, Creactive …

Mechanisms in blood-brain barrier opening and metabolism-challenged cerebrovascular ischemia with emphasis on ischemic stroke

S Sarvari, F Moakedi, E Hone, JW Simpkins… - Metabolic brain disease, 2020 - Springer
… of stroke. In this review article, given our past findings of mechanisms underlying BBB
opening in stroke … in BBB permeability after ischemic stroke. The contribution of each factor to …

Oxidative stress–assassin behind the ischemic stroke

H Pradeep, JB Diya, S Shashikumar… - Folia …, 2012 - termedia.pl
ischemic stroke and catastrophes that set up as an aftermath of the trauma. … ischemic stroke
in patients [8]. This emphasises that the molecular mechanisms of ROS signalling after stroke

Inflammation and infection in clinical stroke

HCA Emsley, PJ Tyrrell - Journal of Cerebral Blood Flow & …, 2002 - journals.sagepub.com
… the majority of ischemic stroke in humans, is an inflammatory process. Complex … inflammatory
mechanisms both in the periphery and in the CNS. Central nervous system inflammation

Cell Type‐Specific Mechanisms in the Pathogenesis of Ischemic Stroke: The Role of Apoptosis Signal‐Regulating Kinase 1

SY Cheon, EJ Kim, JM Kim… - Oxidative Medicine and …, 2018 - Wiley Online Library
… In this review, we will address the underlying pathophysiology of ischemic stroke briefly,
focusing on cell type-specific mechanisms generated from preclinical ischemic stroke models. …