Inflammation and infection in clinical stroke

HCA Emsley, PJ Tyrrell - Journal of Cerebral Blood Flow & …, 2002 - journals.sagepub.com
… the majority of ischemic stroke in humans, is an inflammatory process. Complex … inflammatory
mechanisms both in the periphery and in the CNS. Central nervous system inflammation

Cell Type‐Specific Mechanisms in the Pathogenesis of Ischemic Stroke: The Role of Apoptosis Signal‐Regulating Kinase 1

SY Cheon, EJ Kim, JM Kim… - Oxidative Medicine and …, 2018 - Wiley Online Library
… In this review, we will address the underlying pathophysiology of ischemic stroke briefly,
focusing on cell type-specific mechanisms generated from preclinical ischemic stroke models. …

Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Q Tuo, S Zhang, P Lei - Medicinal research reviews, 2022 - Wiley Online Library
… Therefore, we hope to illustrate the potential tractable target by reviewing our current
understanding of the mechanisms of neuronal death in ischemic stroke, as well as the recent …

[HTML][HTML] Microglia and ischemic stroke: a double-edged sword

AR Patel, R Ritzel, LD McCullough… - International journal of …, 2013 - ncbi.nlm.nih.gov
… Activation of microglia is normally held in check by strictly controlled mechanisms involving
neuronal-glial communication. Ischemic stroke is a powerful stimulus that disables the …

Sex differences in neuroinflammation and neuroprotection in ischemic stroke

MS Spychala, P Honarpisheh… - Journal of …, 2017 - Wiley Online Library
… to stroke or to diseases that affect the brain. This review highlights identified sex differences
in ischemic stroke in … In general, inflammatory mechanisms aim to clear pathogenic cells. The …

Pro-inflammatory and anti-inflammatory cytokines in acute ischemic stroke and their relation to early neurological deficit and stroke outcome

VB Kes, AM Simundic, N Nikolac, E Topic… - Clinical Biochemistry, 2008 - Elsevier
… a negative feedback mechanism to limit production of pro-inflammatory cytokines in ischemic
stroke. Vila et al. have observed no difference in IL-10 levels between stroke patients and …

A review of neuroinflammatory mechanisms in ischemic stroke: background and therapeutic approaches

A Sas, L Horváth, C Oláh, A Valikovics - Mech Neuroinflam, 2017 - books.google.com
… In this review, we will discuss the relevant clinical details of acute ischemic stroke and its …
and cell biology of immunological mechanisms of ischemic stroke, we will introduce the main …

Exploring the hub mechanisms of ischemic stroke based on protein-protein interaction networks related to ischemic stroke and inflammatory bowel disease

W Hu, P Li, N Zeng, S Tan - Scientific reports, 2023 - nature.com
… related to ischemic stroke and inflammatory bowel disease. … network for ischemic stroke and
inflammatory bowel disease, … on inflammatory bowel disease and ischemic stroke from the …

Cerebral edema after ischemic stroke: Pathophysiology and underlying mechanisms

Y Gu, C Zhou, Z Piao, H Yuan, H Jiang, H Wei… - Frontiers in …, 2022 - frontiersin.org
… and even lead to poor outcomes in ischemic stroke. Therefore, more studies are needed to
explore the mechanisms of inflammatory response of cerebral edema after ischemic stroke. …

Pathophysiology, treatment, and animal and cellular models of human ischemic stroke

TM Woodruff, J Thundyil, SC Tang, CG Sobey… - Molecular …, 2011 - Springer
… Novel injury mechanisms Recent experimental studies have shown several novel mechanisms
to also play a role in ischemic stroke-induced brain injury. Our groups have shown that a …